Results 11 to 20 of about 42,696 (223)

Diagnostic utility and pitfalls of human T-lymphotropic virus serology in adult T-cell leukemia/lymphoma: evidence from a 25-year pathology-based nonendemic cohort. [PDF]

J Pathol Clin Res
Abstract Adult T‐cell leukemia/lymphoma (ATLL) is a distinct type of peripheral T‐cell lymphoma (PTCL) driven by human T‐lymphotropic virus type I (HTLV‐1)–infected T cells, but diagnosis can be confounded by histological overlap with non‐ATLL PTCL. While molecular testing is the diagnostic gold standard in endemic areas, HTLV‐1/2 serology is often ...
Yuan CT, Sun LY, Chuang SS, Karube K, Yang HB, Lee SH, Wang RC, Chang KC, Kao CJ, Huang HH, Chou WC.   +10 more
europepmc   +2 more sources

Gut Microbiome Dysbiosis is Associated With Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection and Disease Progression to HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Cross-Sectional Study. [PDF]

Smart Med
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Fernandes LA, de Souza AO, Nukui Y, Marcusso RM, de Oliveira ACP, Casseb J, Clissa PB, Villas-Boas SG, Sanabani SS.   +8 more
europepmc   +2 more sources

Pre-morbid human T-lymphotropic virus type I proviral load, rather than percentage of abnormal lymphocytes, is associated with an increased risk of aggressive adult T-cell leukemia/lymphoma

Haematologica, 2013
Out of 153 newly referred human T-lymphotropic virus type I infected patients, 42 (27%) had 5% or more abnormal lymphocytes, consistent with the diagnosis of smoldering adult T-cell leukemia/lymphoma.
Andrew Hodson, Daniel J. Laydon, Barbara J. Bain, Paul A. Fields, Graham P. Taylor   +4 more
doaj   +1 more source

Pain prevalence, characteristics and associated factors in human T-cell lymphotropic virus type 1 infected patients: a systematic review of the literature

Brazilian Journal of Infectious Diseases, 2016
Objective: To describe the pain in patients infected with human T-cell lymphotropic virus type 1, clinically and epidemiologically. Methods: This systematic review was based on The PRISMA Statement.
Daniel Lordelo San-Martin, Dislene Nascimento dos Santos, Abrahão Fontes Baptista   +2 more
doaj   +1 more source

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]

, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas, Hoelzer, Dieter (Prof. Dr.), Hummel, Michael, Schwartz, Stefan, Thiel, Eckhard   +4 more
core   +2 more sources

Variant Human T-cell Lymphotropic Virus Type 1c and Adult T-cell Leukemia, Australia

Emerging Infectious Diseases, 2013
Human T-cell lymphotropic virus type 1 is endemic to central Australia among Indigenous Australians. However, virologic and clinical aspects of infection remain poorly understood.
Lloyd Einsiedel, Olivier Cassar, Peter Bardy, Daniel Kearney, Antoine Gessain   +4 more
doaj   +1 more source

Loss of correlation between HIV viral load and CD4+ T-cell counts in HIV/HTLV-1 co-infection in treatment naive Mozambican patients [PDF]

, 2009
Seven hundred and four HIV-1/2-positive, antiretroviral therapy (ART) naïve patients were screened for HTLV-1 infection. Antibodies to HTLV-1 were found in 32/704 (4.5%) of the patients.
Augusto, O, Bhatt, N B, Bila, D, Di Mattei, P, Garsia, R, Gudo, E S, Jani, I V, Semá, C   +7 more
core   +2 more sources

High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]

, 2015
BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain, A Gessain, AH Smith, AM Vine, CR Bangham, D Weycker, E Gotuzzo, EL Murphy, F Okada, Graham P Taylor, H Kawai, H Merle, H Nakamura, IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, J Crofton, JR Orland, K Nishioka, L Einsiedel, L Einsiedel, L Einsiedel, L LaGrenade, M Nagai, M Nakagawa, M Osame, M Sugimoto, M Sugimoto, MA Demontis, MG Flynn, OS Morgan, PJ McShane, S Mita, S Mori, Shohreh Honarbakhsh, T Arakaki, T Kondo, T Matsuda, T Yamashiro, W Matsuyama   +37 more
core   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Laboratory diagnosis of human T-lymphotropic virus in Brazil: assays, flowcharts, challenges, and perspectives

Revista da Sociedade Brasileira de Medicina Tropical, 2021
INTRODUCTION We present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil.
Adele Caterino-de-Araujo, Edel Figueiredo Barbosa-Stancioli, José Boullosa Alonso Neto, Mayra Gonçalves Aragón, Bernardo Galvão-Castro, Ricardo Ishak, Carolina Rosadas   +6 more
doaj   +1 more source