Results 91 to 100 of about 39,632 (214)

Human T-lymphotropic virus type 1 infection and disease in Spain

AIDS, 2017
: Human T-lymphotropic virus type 1 (HTLV-1) infection is a neglected disease despite roughly 15 million people are chronically infected worldwide. Lifelong less than 10% of carriers develop life-threatening diseases, mostly a subacute myelopathy known as tropical spastic paraparesis (TSP) and a lymphoproliferative disorder named adult T-cell leukemia (
Mendoza, Carmen de, Caballero, Estrella, Aguilera, Antonio, Requena, Silvia, Ortiz de Lejarazu, Raúl, Pirón, María, González, Rocío, Jiménez, Ana, Roc, Lourdes, Treviño, Ana, Benito, Rafael, Fernández-Alonso, Miriam, Aguinaga, Aitziber, Rodríguez, Carmen, García-Costa, Juan, Blanco, Lidia, Ramos, José M., Calderón, Enrique J., Eirós, José M., Sauleda, Silvia, Barreiro, Pablo, Soriano, Vicente   +21 more
openaire   +3 more sources

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source

Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission [PDF]

, 2013
Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-
Afonso, PV, Brady, JN, Cachat, A, Chevalier, SA, Gessain, A, Mahieux, R, Pise-Masison, CA, Turpin, J   +7 more
core   +1 more source

Self-Flagellation as Possible Route of Human T-Cell Lymphotropic Virus Type-1 Transmission

Emerging Infectious Diseases, 2019
We report human T-cell lymphotropic virus type 1 infection associated with self-flagellation in 10 UK residents. These persons were heterosexual men from Pakistan, India, and Iraq.
Alice R. Tang, Graham P. Taylor, Divya Dhasmana   +2 more
doaj   +1 more source

Infective dermatitis‐like lesions as a novel skin manifestation of systemic lupus erythematosus

Clinical Case Reports, 2020
We describe a unique case of human T‐lymphotropic virus 1 (HTLV‐1)‐associated infective dermatitis‐like lesions in systemic lupus erythematosus. This suggests that some lupus patients may have immunological abnormalities resembling to those described in ...
Margot Raynal, Laure Frumholtz, Lionel Galicier, Anne Saussine, Marie‐Dominique Vignon‐Pennamen, Maxime Battistella, Martine Bagot, Michel Rybojad, Jean‐David Bouaziz   +8 more
doaj   +1 more source

Molecular characterization of human T-cell lymphotropic virus type 1 full and partial genomes by Illumina massively parallel sequencing technology. [PDF]

, 2014
Background\ud \ud Here, we report on the partial and full-length genomic (FLG) variability of HTLV-1 sequences from 90 well-characterized subjects, including 48 HTLV-1 asymptomatic carriers (ACs), 35 HTLV-1-associated myelopathy/tropical spastic ...
Alsanabani, Sabri Saeed Mohammed, Casseb, Jorge Simão do Rosário, Nukui, Youko, Oliveira, Augusto César Penalva de, Pereira, Juliana, Pêssoa, Rodrigo, Segurado, Aluisio Augusto Cotrim, Watanabe, Jaqueline Tomoko   +7 more
core   +3 more sources

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah, Emmanuel Addai Gyabaah, Moro Amidu, Zhao Cheng, Fazlur Rahman Talukdar   +4 more
wiley   +1 more source

Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]

, 2019
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid, Couck, Liesbeth, Favoreel, Herman, Laval, Kathlyn, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +7 more
core   +1 more source

The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators [PDF]

, 2013
The activation of CD4(+) T helper cells is strictly dependent on the presentation of antigenic peptides by MHC class II (MHC-II) molecules. MHC-II expression is primarily regulated at the transcriptional level by the AIR-1 gene product CIITA (class II ...
Abdallah, R., Accolla, Roberto, Forlani, Greta, Tosi, Giovanna   +3 more
core   +2 more sources

Prevalence of Human T-Lymphotropic Virus Types I and II in Patients With Hematological Disorders in Isfahan, Iran [PDF]

, 2015
Background: Human T-cell lymphotropic virus types I and II (HTLV-I and HTLV-II) are deltaretroviruses which may cause leukemia, lymphoma and HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Ghorani, Mohammadreza., Karimi, Ali., Mahzoonieh, Mohamad Reza., Nikoozad, Razieh., Pourgheysari, Batoul.   +4 more
core   +3 more sources