Results 31 to 40 of about 26,257 (175)

SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction: The human-T cell lymphotropic virus is a retrovirus with various types known so far. HTLV-I and HTLV-II are of clinically importance as they cause different diseases such as adult T-cell leukemia/lymphoma, tropical spastic paraparesis, and ...
Manuela Muñoz, Santiago Carvalho, Jorge Hernando Donado, Gloria Eugenia Barco, Sergio Jaramillo   +4 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Seroprevalence of Human T-cell Lymphotropic Virus Types I/II Among Blood Donors in a Tertiary Hospital in Oman

Oman Medical Journal
Objectives: Routine blood donor screening of human T-cell lymphotropic virus (HTLV) has been practiced in Oman since 2017. Limited data exists on HTLV seroprevalence among Omanis.
Noora Al-Bulushi, Khuloud Al Maamari, Fatma Ba Alawi, Arwa Z. Al-Riyami, Ali Al Marhoobi   +4 more
doaj   +1 more source

Sexual transmission of human T-cell lymphotropic virus type 1

Revista da Sociedade Brasileira de Medicina Tropical, 2014
Human T-cell lymphotropic virus type 1 (HTLV-1) is endemic in many parts of the world and is primarily transmitted through sexual intercourse or from mother to child.
Arthur Paiva, Jorge Casseb
doaj   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

Transfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira, Anna S. Nishyia, Jerenice E. Ferreira, Claudia Di Lorenzo Oliveira, Cesar de Almeida‐Neto, Tila Fanciani, Katia C. Dantas, Juliana Derriga, Silvia Petrossi Gallo Polato, Nanci Salles, Vanderson Rocha, Alfredo Mendrone‐Junior   +11 more
wiley   +1 more source

Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

Nature Communications, 2020
Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.
Michał S. Barski, Jordan J. Minnell, Zuzana Hodakova, Valerie E. Pye, Andrea Nans, Peter Cherepanov, Goedele N. Maertens   +6 more
doaj   +1 more source

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures

Nature Communications, 2021
Human T-cell lymphotropic virus type 1 (HTLV-1) is an oncogenic deltaretrovirus. Here the authors provide structural characterization of the binding mechanism of novel integrase strand transfer inhibitor (INSTI) candidates to limit HTLV-1 infection.
Michal S. Barski, Teresa Vanzo, Xue Zhi Zhao, Steven J. Smith, Allison Ballandras-Colas, Nora B. Cronin, Valerie E. Pye, Stephen H. Hughes, Terrence R. Burke, Peter Cherepanov, Goedele N. Maertens   +10 more
doaj   +1 more source

A Machine Learning Approach for MicroRNA Precursor Prediction in Retro-transcribing Virus Genomes

Journal of Integrative Bioinformatics, 2016
Identification of microRNA (miRNA) precursors has seen increased efforts in recent years. The difficulty in experimental detection of pre-miRNAs increased the usage of computational approaches. Most of these approaches rely on machine learning especially
Demirci Müşerref Duygu Saçar, Toprak Mustafa, Allmer Jens   +2 more
doaj   +1 more source

Implementation of nationwide screening of pregnant women for HTLV-1 infection in Japan: analysis of a repeated cross-sectional study

BMC Public Health, 2020
Background Screening of pregnant women carrying human T-lymphotropic virus type 1 (HTLV-1) has a crucial role in reducing the number of HTLV-1 carriers. A national HTLV-1 screening program for pregnant women was started in 2011 in Japan.
Naohiro Yonemoto, Shunji Suzuki, Akihiko Sekizawa, Shinichi Hoshi, Yoko Sagara, Kazuo Itahashi   +5 more
doaj   +1 more source