Results 61 to 70 of about 47,265,557 (210)

Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei, Mahdi Khosravi Nia, Kasra Allaei Rouzbahani, Maryam Kazemi, Negar Asghari Hosori, Mehdi Norouzi, Farzaneh Sotoudegan, Narges Eslami, Negar Ariamand, Vahid Shahnavaz, Arash Letafati, Sayed‑Hamidreza Mozhgani   +11 more
wiley   +1 more source

Induction of cytolytic T lymphocytes directed towards the V3 loop of the human immunodeficiency virus type 1 external glycoprotein gp120 by p55gag/V3 chimeric vaccinia viruses [PDF]

, 1993
T cell-mediated cytotoxicity may play an important role in controlling infection by human immunodeficiency virus (HIV). In order to study the ability of rationally designed antigens to induce cytolytic T lymphocytes (CTLs) we replaced stretches of 30 to ...
Deml, Ludwig, Böltz, T., Wagner, Ralf, Modrow, Susanne, Wolf, Hans J.   +4 more
core   +1 more source

Low Prevalence of Human T‐Cell Lymphotropic Virus Type 1 (HTLV‐1) in a Hospital Triage Population in Tehran During 2024–2025

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Human T‐cell lymphotropic virus type 1 (HTLV‐1) is a retrovirus that is associated to adult T‐cell leukemia/lymphoma (ATLL) and HTLV‐1–associated myelopathy/tropical spastic paraparesis (HAM/TSP) as two major diseases of the virus.
Arash Letafati, Shima Sadeghipour Marvi, Negar Asghari Hosori, Ghazale Molaverdi, Alireza Esfandiari, Nima Afshar Moghadam, Shabnam Siavoshi, Mehdi Norouzi, Sayed‐Hamidreza Mozhgani   +8 more
wiley   +1 more source

Utility of Flow Cytometry for Prognostic Prediction in Adult T‐Cell Leukemia/Lymphoma

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Adult T‐cell leukemia/lymphoma (ATL) exhibits marked clinical heterogeneity; however, current classification primarily rely on morphology and laboratory findings and require further advancement. This study aimed to evaluate the roles of human T‐lymphotropic virus type 1 (HTLV‐1)–infected cell (CD4‐positive T cell) analysis system ...
Shigeo Fuji, Masahito Tokunaga, Lucy Cook, Atae Utsunomiya, Junya Makiyama, Youko Suehiro, Ki‐Ryang Koh, Makoto Nakashima, Yoshihisa Yamano, Kaoru Uchimaru   +9 more
wiley   +1 more source

The influence of human T lymphotropic virus type I infection on the outcome of cardiovascular surgery [PDF]

, 2000
Objective: Human T lymphotropic virus type I infects CD4+ T cells and affects cell-mediated immunity. Cardiopulmonary bypass transiently alters lymphocyte subsets, resulting in a reduction in CD4+ T cells and an increase in CD8+ T cells. We proposed that
Masuda, Hiroshi, Iguro, Yoshifumi, Watanabe, Shun-ichi, Hisatomi, Kouichi, Toda, Riichiro, Shimokawa, Shinji, Moriyama, Yukinori, Matsumoto, Hitoshi, Taira, Akira   +8 more
core   +1 more source

ACUTE ENCEPHALOPATHY IN AN ELDERLY PATIENT WITH HTLV-1 DETECTED IN CEREBROSPINAL FLUID BY PCR: CASE REPORT

Brazilian Journal of Infectious Diseases
Acute encephalopathies in elderly individuals represent a diagnostic challenge, especially when associated with uncommon viral infections such as Human T-cell Lymphotropic Virus Type 1.
Manoella de Miranda da Silva, Luiza Heinzen, Henry Liszczynski, Sabrina Sabino, Allan Henrique Cordeiro   +4 more
doaj   +1 more source

A Snapshot of the UK Blood Donor Plasma Virome: A Retrospective Cross‐Sectional Cohort Study

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Estimates of population prevalence and genetic diversity of bloodborne viruses in healthy humans are essential to support population‐scale monitoring for transfusion transmission risk. In the UK and globally, blood donations are routinely screened for a limited number of high‐consequence pathogens, but the full composition of the plasma virome
Kai Kean, Richard M. Mayne, Kaitlin Reid, Shannah Secret, Belinda K. Singleton, Rebecca Rockett, Piya Rajendra, Heli Harvala, Judith Breuer, M. Azim Ansari, Katrina Lythgoe, Peter Simmonds, Tanya Golubchik   +12 more
wiley   +1 more source

Clonal origin of Epstein-Barr virus-infected T/NK-cell subpopulations in chronic active Epstein-Barr virus infection [PDF]

, 2010
Clonal expansion of Epstein-Barr virus (EBV) infected B-cells occasionally occurs in immunocompromized subjects. EBV-infected T/natural killer (NK)-cells proliferate in patients with chronic active EBV infection (CAEBV) that is a rare mononucleosis ...
Tamami Tanaka, Ken-Ichi Imadome, Toshihiro Miyamoto, Koichi Akashi, Hidetoshi Takada, Koichi Ohshima, Yasunobu Abe, Toshiro Hara, Shouichi Ohga, Masataka Ishimura, Goichi Toshimoto   +10 more
core  

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects

Viruses, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Benjamin Usadi, Roberta Bruhn, Jue Lin, Tzong-Hae Lee, Elizabeth Blackburn, Edward L. Murphy   +5 more
doaj   +1 more source

Virus Markers Associated with Vertical Transmission of Human T Lymphotropic Virus Type 1 in Jamaica [PDF]

Clinical Infectious Diseases, 2002
In a prospective study involving 150 mothers and their offspring in Jamaica, we examined maternal viral factors associated with the risk of transmission of human T lymphotropic virus type 1 (HTLV-1). Overall, the incidence of HTLV-1 infection among children was 8.3 occurrences per 1000 person-months. A higher maternal provirus level (odds ratio [OR], 1.
Michie, Hisada, Elizabeth M, Maloney, Takashi, Sawada, Wendell J, Miley, Paulette, Palmer, Barrie, Hanchard, James J, Goedert, Angela, Manns   +7 more
openaire   +2 more sources