Results 141 to 150 of about 238,440 (280)

Neutrophil Macrophage Crosstalk via Extracellular Vesicles Drives Reverse Migration in a Fully Human Model of Wound Healing

open access: yesAdvanced Science, EarlyView.
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde   +5 more
wiley   +1 more source

Human trafficking and the growing malady of disinformation. [PDF]

open access: yesFront Public Health, 2022
Prakash J, Erickson TB, Stoklosa H.
europepmc   +1 more source

An Ile-568 to Asn Polymorphism Prevents Normal Trafficking and Function of the Human P2X7 Receptor [PDF]

open access: hybrid, 2003
James S. Wiley   +9 more
openalex   +1 more source

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

open access: yesAdvanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li   +11 more
wiley   +1 more source

Human Trafficking Education: A Pilot Study of Integration into Medical School Curriculum. [PDF]

open access: yesJ Med Educ Curric Dev, 2023
Das DM   +7 more
europepmc   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

open access: yesAdvanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang   +8 more
wiley   +1 more source

A Case of Human Trafficking in Appalachia and What Emergency Physicians Can Learn from It. [PDF]

open access: yesWest J Emerg Med, 2023
Jarrell KL   +6 more
europepmc   +1 more source

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