Results 141 to 150 of about 9,000,670 (290)

Evaluating the applicability of replication success metrics in animal-to-human translation: A simulation study. [PDF]

Elife
Huang CJ, Pawel S, Wever KE, Ineichen BV, Heyard R.   +4 more
europepmc   +2 more sources

Comparative effectiveness of implementation strategies for Accelerating Cervical Cancer Elimination through the integration of Screen-and-treat Services (ACCESS study): protocol for a cluster randomized hybrid type III trial in Nigeria

Implementation Science
Background Despite the increased risk of cervical cancer (CC) among women living with HIV (WLHIV), CC screening and treatment (CCST) rates remain low in Africa.
Babayemi O. Olakunde, Ijeoma U. Itanyi, John O. Olawepo, Lin Liu, Chinenye Bembir, Ngozi Idemili-Aronu, Nwamaka N. Lasebikan, Tonia C. Onyeka, Cyril C. Dim, Chibuike O. Chigbu, Echezona E. Ezeanolue, Gregory A. Aarons   +11 more
doaj   +1 more source

Production of human translation-competent lysates using dual centrifugation. [PDF]

RNA Biol, 2022
Gurzeler LA, Ziegelmüller J, Mühlemann O, Karousis ED.   +3 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Comparison of absorbed dose extrapolation methods for mouse-to-human translation of radiolabelled macromolecules. [PDF]

EJNMMI Res, 2022
Cicone F, Viertl D, Denoël T, Stabin MG, Prior JO, Gnesin S.   +5 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Bridging SMT and TM with translation recommendation [PDF]

, 2010
We propose a translation recommendation framework to integrate Statistical Machine Translation (SMT) output with Translation Memory (TM) systems. The framework recommends SMT outputs to a TM user when it predicts that SMT outputs are more suitable for ...
He, Yifan, Way, Andy, van Genabith, Josef, Ma, Yanjun   +3 more
core  

A Structured Approach to Optimizing Animal Model Selection for Human Translation: The Animal Model Quality Assessment. [PDF]

ILAR J, 2021
Storey J, Gobbetti T, Olzinski A, Berridge BR.   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Le Petit Prince Hong Kong (LPPHK): Naturalistic fMRI and EEG data from older Cantonese speakers

Scientific Data
Currently, the field of neurobiology of language is based on data from only a few Indo-European languages. The majority of this data comes from younger adults neglecting other age groups. Here we present a multimodal database which consists of task-based
Mohammad Momenian, Zhengwu Ma, Shuyi Wu, Chengcheng Wang, Jonathan Brennan, John Hale, Lars Meyer, Jixing Li   +7 more
doaj   +1 more source