Results 191 to 200 of about 9,000,670 (290)

An Active Inference Agent for Modeling Human Translation Processes. [PDF]

Entropy (Basel)
Carl M.
europepmc   +1 more source

Utilizing rat kidney gene co-expression networks to enhance safety assessment biomarker identification and human translation. [PDF]

iScience
Kunnen SJ, Callegaro G, Sutherland JJ, Trairatphisan P, van Kessel HW, Wijaya LS, Chung G, Pye K, Goldstein KM, Teague CR, Fisher CP, Saez-Rodriguez J, Brown C, Elmore SA, Heinz-Taheny KM, Stevens JL, van de Water B.   +16 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Neuronal oscillations in cognition: Down syndrome as a model of mouse to human translation. [PDF]

Neuroscientist
Chang P, Pérez-González M, Constable J, Bush D, Cleverley K, Tybulewicz VLJ, Fisher EMC, Walker MC.   +7 more
europepmc   +1 more source

Translation as Inquiry: An approach to the Humanities Translations

The Journal of Translation Studies, 2009
openaire   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Quantitative profiling of human translation initiation reveals elements that potently regulate endogenous and therapeutically modified mRNAs. [PDF]

Mol Cell
Lewis CJT, Xie LH, Bhandarkar SM, Jin D, Abdallah K, Draycott AS, Chen Y, Thoreen CC, Gilbert WV.   +8 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Which experimental factors govern successful animal-to-human translation in multiple sclerosis drug development? A systematic review and meta-analysis. [PDF]

EBioMedicine
Berg I, Härvelid P, Zürrer WE, Rosso M, Reich DS, Ineichen BV.   +5 more
europepmc   +1 more source