Results 91 to 100 of about 2,549,371 (292)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Testing the limits of human vision with quantum states of light: past, present, and future experiments

open access: yes, 2018
The human eye contains millions of rod photoreceptor cells, and each one is a single-photon detector. Whether people can actually see a single photon, which requires the rod signal to propagate through the rest of the noisy visual system and be perceived
Holmes, Rebecca M.   +3 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Local Parallel Cross Pattern: A Color Texture Descriptor for Image Retrieval

open access: yesSensors, 2019
Riding the wave of visual sensor equipment (e.g., personal smartphones, home security cameras, vehicle cameras, and camcorders), image retrieval (IR) technology has received increasing attention due to its potential applications in e-commerce, visual ...
Qinghe Feng   +5 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Attentional load and sensory competition in human vision: Modulation of fMRI responses by load fixation during task-irrelevant stimulation in the peripheral visual field. [PDF]

open access: yes, 2005
Perceptual suppression of distractors may depend on both endogenous and exogenous factors, such as attentional load of the current task and sensory competition among simultaneous stimuli, respectively. We used functional magnetic resonance imaging (fMRI)
Dolan, R.J.   +5 more
core  

Deep Learning Scooping Motion using Bilateral Teleoperations

open access: yes, 2018
We present bilateral teleoperation system for task learning and robot motion generation. Our system includes a bilateral teleoperation platform and a deep learning software.
Harada, Kensuke   +5 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Pairwise-Distance-Analysis-Driven Dimensionality Reduction Model with Double Mappings for Hyperspectral Image Visualization

open access: yesRemote Sensing, 2015
This paper describes a novel strategy for the visualization of hyperspectral imagery based on the analysis of image pixel pairwise distances. The goal of this approach is to generate a final color image with excellent interpretability and high contrast ...
Yi Long   +4 more
doaj   +1 more source

Fast, invariant representation for human action in the visual system [PDF]

open access: yes, 2016
Humans can effortlessly recognize others' actions in the presence of complex transformations, such as changes in viewpoint. Several studies have located the regions in the brain involved in invariant action recognition, however, the underlying neural ...
Isik, Leyla   +2 more
core   +1 more source

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