Results 61 to 70 of about 2,548,447 (289)

What horses and humans see: a comparative review [PDF]

, 2009
Adaptations of the mammalian eye have tailored each to its own particular ecological niche. On the one hand, it would appear that the horse is best served by a system that can keep "half an eye" on everything, while the human benefits from focussing on ...
Arkins, S, Hall, CA, Murphy, J
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

MAGNet: A Camouflaged Object Detection Network Simulating the Observation Effect of a Magnifier

Entropy, 2022
In recent years, protecting important objects by simulating animal camouflage has been widely employed in many fields. Therefore, camouflaged object detection (COD) technology has emerged.
Xinhao Jiang, Wei Cai, Zhili Zhang, Bo Jiang, Zhiyong Yang, Xin Wang   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Just noticeable distortion model based on entropy masking in DCT domain

Dianxin kexue, 2023
In order to improve the threshold accuracy of JND (just noticeable distortion) model in DCT (discrete cosine transform) domain and avoid cross-domain operation, entropy masking effect was introduced into DCT-based JND model.Firstly, starting from the ...
Qionghua LUO, Hongkui WANG, Haibing YIN, Yafen XING   +3 more
doaj  

Representation of White- and Black-Box Adversarial Examples in Deep Neural Networks and Humans: A Functional Magnetic Resonance Imaging Study

, 2019
The recent success of brain-inspired deep neural networks (DNNs) in solving complex, high-level visual tasks has led to rising expectations for their potential to match the human visual system.
Han, Chihye, Kim, Daeshik, Kwon, Gihyun, Nam, Seungkyu, Yoon, Wonjun   +4 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Multiparameter vision testing apparatus [PDF]

, 1975
Compact vision testing apparatus is described for testing a large number of physiological characteristics of the eyes and visual system of a human subject.
Homkes, R. J., Hunt, S. R., Jr., Poteate, W. B., Sturgis, A. C.   +3 more
core   +1 more source

Priming Neural Networks

, 2017
Visual priming is known to affect the human visual system to allow detection of scene elements, even those that may have been near unnoticeable before, such as the presence of camouflaged animals.
Biparva, Mahdi, Rosenfeld, Amir, Tsotsos, John K.   +2 more
core   +1 more source