Results 121 to 130 of about 223,141 (305)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Dynamics of Humanitarian Diplomacy During Wartime: Insights from Tigray Crisis in Ethiopia

Social Sciences
This study examines the role of humanitarian diplomacy during the Tigray humanitarian crisis in Ethiopia, a humanitarian disaster marked by severe shortages in food, healthcare, and essential services that deeply affect civilians.
Mulubrhan Atsbaha Geremedhn, Hafte Gebreselassie Gebrihet   +1 more
doaj   +1 more source

A simulation approach for collaborative humanitarian aid distribution management: the case of Bogotá city. [PDF]

Heliyon, 2022
Guzmán-Cortés DC, Gonzaléz-Rodríguez L, Franco C, Guerrero WJ.   +3 more
europepmc   +1 more source

Building a new life in Australia: introducing the longitudinal study of humanitarian migrants [PDF]

Introduces a study aimed to shed light on the settlement pathways and outcomes of newly arrived humanitarian migrants, focusing particularly on the factors that promote or hinder a successful transition.
Diana Smart, John De Maio, Michelle Silbert, Rebecca Jenkinson   +3 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The humanitarian aid of neurosurgical missions in Peru: A chronicle and future perspectives. [PDF]

Surg Neurol Int, 2022
Bocanegra-Becerra JE, Castillo-Huerta NM, Ludeña-Esquivel A, Torres-García ON, Vilca-Salas MI, Bermudez-Pelaez MF.   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

How do international humanitarian aid workers stay healthy in the face of adversity? [PDF]

PLoS One, 2022
De Jong K, Martinmäki S, Brake HT, Kleber R, Haagen J, Komproe I.   +5 more
europepmc   +1 more source

Making the Food Aid Convention meet the realities of the 21st century [PDF]

Emergency situations have become increasingly frequent over the past 25 years, often coupled with acute and chronic food insecurity in the affected countries.
FAO Economic and Social Development Department
core   +1 more source