Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The Relationship between Humanitarian Assistance and Aid for Development in the United Nations [PDF]
Revista CIDOB d'Afers Internacionals, 1998 The present study deals with the close relationship between humanitarian assistance operations and aid for development and their incidence in the guidelines and activities of the United Nations. The starting point of the analysis of the current standards
Helena Torroja Mateu
doaj
Responsible exit of humanitarian aid agencies at the end of programmes: a scoping review protocol. [PDF]
BMJ Open, 2023 Bahati D, Sy H, Kalhor A, Marchal B.
europepmc +1 more source
The state of humanitarian funding [PDF]
, 2007 Is the pot of humanitarian finance able to meet present andprojected global humanitarian needs? Does money followneed? Do existing financing mechanisms promote quality,context-specific, timely and evidence-based aid?
Kevin Pepper, Peter Walker
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Hitit Sosyal Bilimler DergisiIn recent years, extraordinary situations and humanitarian crises have increased the number of studies in the field of humanitarian aid logistics.
Gülşah Ayvazoğlu, İskender Peker
doaj +1 more source
Characteristics of humanitarian aid in a developed country: Israel Defense Force's experience from the Türkiye -Syria earthquake. [PDF]
J Glob Health, 2023 Nitecki M, Ohayon S, Almog O.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Logistics Information and Knowledge Management Issues in Humanitarian Aid Organizations [PDF]
In this paper, we assess the need for logistics information and knowledge management in humanitarian aid organizations. To do so, we combine literature sources with an extensive case study that we conducted at Médecins sans Frontières–Holland, which ...
Brito, M.P. de +2 more
core +1 more source
Humanitarian effectiveness in complex emergencies: South Sudan and Darfur
, 2014 My Master‟s Thesis explores the extent to which the international community has established processes of evaluation and learning that are improving humanitarian responses to complex humanitarian emergencies over time.
Jirouskova, Pavlina
core +2 more sources