Results 141 to 150 of about 1,336,644 (348)

Beyond aid: Sustainable responses to meeting language communication needs in humanitarian contexts [PDF]

, 2021
Barbara Moser‐Mercer, Somia Qudah, Mona Malkawi, Jayne Mutiga, Mohammed Al‐Batineh   +4 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Health trajectories of international humanitarian aid workers: growth mixture modelling findings from a prospective cohort study. [PDF]

BJPsych Open, 2023
de Jong K, Martinmäki SE, Te Brake H, Komproe I, Kleber RJ, Haagen JFG.   +5 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Moral injury among humanitarian aid personnel: a preliminary examination of associations with rumination and mental health

Journal of International Humanitarian Action
Given high rates of poor mental health among humanitarian aid workers, there has been a strong push for more research identifying risk and protective factors tied to poor mental health among this at-risk population.
Adrian J. Bravo, Michael F. Drusano, Madi Williamson, Rebecca J. Dunaief, Rachel Williamson, Gabriela Heermans   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Evolution of Humanitarian Aid in Disasters: Ethical Implications and Future Challenges

Philosophies
Ethical dilemmas affect several essential elements of humanitarian aid, such as the adequate selection of crises to which to provide aid and a selection of beneficiaries based on needs and not political or geostrategic criteria.
Pedro Arcos González, Rick Kye Gan
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The Opinions of Poles about the Need to Provide Humanitarian Aid to Refugees from the Area Covered by the Russian-Ukrainian War. [PDF]

Int J Environ Res Public Health, 2022
Karakiewicz-Krawczyk K, Zdziarski K, Landowski M, Nieradko-Heluszko A, Kotwas A, Szumilas P, Knyszyńska A, Karakiewicz B.   +7 more
europepmc   +1 more source

The Use of 360° Video by International Humanitarian Aid Organizations to Spread Social Messages and Increase Engagement [PDF]

, 2020
Berta García Orosa, Sara Pérez‐Seijo
openalex   +1 more source