Results 101 to 110 of about 2,131,362 (279)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NATO's "humanitarian intervention" in Kosovo: legal precedent or aberration?
, 2009 NATO's intervention in Kosovo in 1999 (Operation Allied Force) is one of the seminal events in contemporary international relations. While the humanitarian aspect of this intervention was widely endorsed the dominant view is that NATO acted illegally ...
Hehir, A.
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Humanitarian Engineering at Mines newsletter, Fall | Winter 2024
"Humanitarian Engineering at Mines: Quarterly Newsletter of the Colorado School of Mines Humanitarian Engineering Program" Vol.4, No.
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Humanitarian Engineering at Mines newsletter November-December 2020
, 2020 "Engineering as it should be.
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Humanitarian Engineering at Mines newsletter, Spring/Summer 2025
"Humanitarian Engineering at Mines: Quarterly Newsletter of the Colorado School of Mines Humanitarian Engineering Program." Spring/Summer 2025 - New Horizons Vol.4, No.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source