Results 81 to 90 of about 175,037 (292)

David Cameron has created a new vision of Conservative foreign policy, one which is far happier to intervene to stop suffering and expounds a bigger, and more liberal, view of Britain’s interests in the world [PDF]

open access: yes, 2013
Tim Oliver and Matt Beech contend that the Conservative Party changed its philosophical approach to humanitarian intervention during its years in opposition.
Beech, Matt, Oliver, Tim
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Analyzing Humanitarian Intervention from an African Point of View

open access: yesVestnik RUDN. International Relations, 2012
The article analyzes the concept of humanitarian intervention from the African perspectives, owing to the none existed of agreed definition or codification of this concept in international law, it has continued to generate considerable interest among ...
- Okoh ThankGod Emeka
doaj  

Humanitarian Intervantion: The Principle of Responsibility to Protect (R2P)

open access: yesJurnal Hubungan Internasional, 2015
This article describes the notion of the Responsibility to Protect (R2P) as a branch of humanitarian intervention. This approach emerges to immediately respond atrocities of innocent people due to political persecution taking place in a state. R2P allows
Muhammad Zahrul Anam
doaj   +1 more source

Conflict Prevention, Management, and Resolution: Africa — Regional Strategies for the Prevention of Displacement and Protection of Displaced Persons: The Cases of the OAU, ECOWAS, SADC, and IGAD [PDF]

open access: yes, 2001
This Article seeks to examine the preparedness of certain African regional actors to protect displaced persons in times of armed conflict, and to prescribe formulas to strengthen the capabilities of such actors.
Levitt, Jeremy
core   +3 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Vacillating on Darfur: responsibility to protect, to prosecute, or to feed? [PDF]

open access: yes, 2009
The international community has responded to the crisis in Darfur in a seemingly haphazard manner. Yet, a closer examination reveals a complex normative environment where states must respond to three related, but sometimes conflicting, sets of human ...
Mills, Kurt
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Humanitarian Intervention: Evolving Norms, Fragmenting Consensus (Remarks) [PDF]

open access: yes, 2014
Traditionally, the evolution of customary international law was understood as a gradual process: in some idealized model, we might see first a few states, and then a few more, implicitly agreeing to follow a practice, and then we would gradually begin to
Brooks, Rosa
core   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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