Results 71 to 80 of about 175,037 (292)

Humanitarian intervention ; you need from prohibition [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2004
مداخله بشر دوستانه از مفاهیمی است که باوجود دارا بودن سابقه‌ای حدودا یکصد ساله در ادبیات حقوق بین‌الملل،تنها در یک دهه اخیر مورد توجه مجامع بین‌المللی و از آن جمله محافل علمی و حقوقی جهان قرار گرفته است و دلیل آن،گسترش توجه‌ به حقوق بنیادین بشر از یک طرف
GHASEM AGHAII
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

NATO’s Military Intervention in Kosovo and the Diplomatic Alternative [PDF]

open access: yes
NATO’s military intervention in Kosovo is a highly controversial issue due to its violation of the general rule in the international law that prohibits the use of force, even in the case of a humanitarian crisis. What is also unique about the Kosovo case
Iulia Elena SOCEA
core   +1 more source

Exploring the Effectiveness of the Human Rights Court in Indonesia: A Call for Humanitarian Action

open access: yesJournal of Liberty and International Affairs
Indonesia’s Human Rights Court, established under Law No. 26/2000, has faced criticism due to persistent unresolved cases, highlighting flaws in its legal foundation.
Ria Wierma Putri   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Kosovo: the implications for humanitarian intervention [PDF]

open access: yesForced Migration Review, 1999
Do NATO’s actions represent an advance or a setback for international order?
Richard Caplan
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

From Nuremberg to Rome and Beyond: The Fight Against Genocide, War Crimes, and Crimes Against Humanity [PDF]

open access: yes, 1999
More than 200 years ago in his work Perpetual Peace, \u27 Immanuel Kant called for peace and human rights to be protected under international law. Ever since, the United Nations, which was founded in 1945 as part of the worldwide fight against tyranny ...
Kastrup, Dieter
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Sekuritisasi dalam Kerangka “R2P” dan Intervensi Kemanusiaan: Dilema Antara Legalitas dan Legitimasi

open access: yesJurnal Hubungan Internasional, 2015
The paper sets off by discussing security concept in IR and securitization process as well as new emerging norms in the frame of “R2P”. Furthermore, this paper also tries to examine closer at legal, ethic also other dilemmas by entering the discourse of ...
Eric Hendra
doaj   +1 more source

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