Results 121 to 130 of about 2,131,362 (279)

Humanitarian Interventions and National Interests; Iraq Case Study

open access: yesتحقيقات جغرافيايی, 2018
Introduction and Background: The idea of human intervention stems from the sense of responsibility of the international community in protecting the population from harming political violence, and this process demonstrates the importance of addressing the
Zohre Heidari Beni   +3 more
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Health and Humanitarian Logistics - Keynote Interview with Sanjay Gupta

open access: yes, 2016
Presented at the 8th Annual Conference on Health and Humanitarian Logistics, August 29-31, 2016, Atlanta, GA.Day 2 - Keynote Speaker Interview with Sanjay GuptaMichelle Nunn, President and CEO, CARE USA.Sanjay Gupta, MD, Chief Medical Correspondent, CNN ...
Nunn, Michelle, Gupta, Sanjay
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

JUSTIFIKASI INTERVENSI INTERNASIONAL DALAM KONFLIK SUATU NEGARA

open access: yesJurnal Asia Pacific Studies, 2017
Conflict among states or interstate conflict is still part of the important concern in the politics and international relations. International attention is becoming stronger along with the shift view of international society regarding the intervention ...
Andaru Satnyoto
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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