Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Jan Paweł II o relacjach między nauką i teologią
Zagadnienia Filozoficzne w Nauce, 2014 The relation between science and religion is a very interesting subject for philosophers, some scientists and rather few theologians. Pope John Paul II did for the understanding of the subject more than any other pope and he still encourages theologians ...
Zbigniew Wolak
doaj
Global Ecologies and the Environmental Humanities: Postcolonial Approaches edited by Elizabeth Deloughrey, Jill Didur, and Anthony Carrigan [PDF]
, 2016 Review of Elizabeth Deloughrey, Jill Didur, and Anthony Carrigan\u27s Global Ecologies and the Environmental Humanities: Postcolonial ...
Bartlett, Joshua
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Understanding the motivations to become a public humanities or social studies secondary school teacher in Singapore: a mixed methods based study [PDF]
, 2022 Kai Xiang Kwa
openalex +1 more source
Expressions, Winter 2014 [PDF]
, 2014 College of Humanities and the Arts Newsletter, Volume
San Jose State University, College of the Humanities and the Arts
core +4 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Effect of Formative Assessment of Objective Questions on the Learning Performance in Nursing Humanities [PDF]
, 2022 Seran Kook
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source