Results 131 to 140 of about 730,113 (317)

PHILOSOPHY AND THE STUDY OF GLOCALIZATION

Glocalism: Journal of Culture, Politics and Innovation
Within the bosom of the humanities philosophy reposes and, as an academic field, it is ever so often criticized for its aloofness. In a recent book, Roudometof and Dessi (2022, 9-10) politely quip that philosophy’s engagement with the “glocal” has been ...
ODYSSEUS MAKRIDIS
doaj   +1 more source

Are 'Human factors' Human? [PDF]

The Computer Journal, 1988
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Pandemic preparedness: why humanities and social sciences matter

Frontiers in Public Health
Whilst many lessons were learned from the COVID-19 pandemic, ongoing reflection is needed to develop and maintain preparedness for future outbreaks.
Sally Frampton, Kingsley Orievulu, Kingsley Orievulu, Kingsley Orievulu, Philippa C. Matthews, Philippa C. Matthews, Philippa C. Matthews, Philippa C. Matthews, Alberto Giubilini, Joshua Hordern, Lizzie Burns, Sean Elias, Ethan Friederich, Nomathamsanqa Majozi, Sam Martin, Sam Martin, Austin Stevenson, Samantha Vanderslott, Janet Seeley, Janet Seeley   +19 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

February 2021 The Humanities at Otterbein: A newsletter of the Humanities Advisory Committee

, 2021
Faculty Focus: Dr. Amy Sheeran, Modern Languages HAC Grants and Opportunities for Spring 2021 Online Event: Study the Humanities with Scott Muir from the National Humanities Alliance Call For Student Submissions To Aegis, Otterbein\u27s Humanities ...
Humanities Advisory Committee,
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Technoapocalypse: the effects of the technological disaster on the human subject in Don DeLillo’s The Silence [PDF]

Currents
Multitudes of apocalyptic visions are based on events of great magnitude, such as a global nuclear war, a catastrophic natural disaster or an invasion from outer space.
Barbara Pawlak
doaj