Results 131 to 140 of about 1,389,305 (312)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Is UK humanities research reaching the widest possible audience? [PDF]

open access: yes, 2014
Report points to 'serious dangers for the international standing of UK research' in humanities and social sciences. Today marks the launch of another report on open access, a topic area that is rapidly becoming saturated.
Eve, Martin Paul
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

PHILOSOPHY AND THE STUDY OF GLOCALIZATION

open access: yesGlocalism: Journal of Culture, Politics and Innovation
Within the bosom of the humanities philosophy reposes and, as an academic field, it is ever so often criticized for its aloofness. In a recent book, Roudometof and Dessi (2022, 9-10) politely quip that philosophy’s engagement with the “glocal” has been ...
ODYSSEUS MAKRIDIS
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Are 'Human factors' Human? [PDF]

open access: yesThe Computer Journal, 1988
openaire   +1 more source

Peer review innovations in Humanities: how can scholars in A&H profit of the "wisdom of the crowds"? [PDF]

open access: yes, 2010
Though supported by a large number of scholars in Scientific, Technical, and Medical (STM) disciplines traditional peer review does not live up to the needs of an efficient scholarly communication system and of quality research control.
Cassella, Maria
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Pandemic preparedness: why humanities and social sciences matter

open access: yesFrontiers in Public Health
Whilst many lessons were learned from the COVID-19 pandemic, ongoing reflection is needed to develop and maintain preparedness for future outbreaks.
Sally Frampton   +19 more
doaj   +1 more source

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