Results 111 to 120 of about 944,399 (257)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Utah Humanities Research Foundation correspondence, 1947-1950
, 1947 A set of letters dated 1947 to 1950 related to the work of the Utah Humanities Research Foundation, particularly the publication of articles in the Utah Humanities Review and Western Humanities Review.
Utah Humanities Research Foundation; Lee, Hector, 1908-1992; Bentley, Harold W.; Polland, Harold F.; Mulder, William
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Humanities, Vol. 9, Num. 6, November/December 1988
, 1988 Featured story: Public Humanities ...
National Endowment for the Humanities, Office of Publications
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Utah Humanities Research Foundation correspondence, 1950-1952
, 1947 A set of letters dated 1947 to 1950 related to the work of the Utah Humanities Research Foundation, particularly the publication of articles in the Utah Humanities Review and Western Humanities Review.
Utah Humanities Research Foundation; Lee, Hector, 1908-1992; Bentley, Harold W.; Folland, Harold F.; Mulder, William
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Humanities, Vol. 13, Num. 5, September/October 1992
, 1992 Featured story: Chairman's Report: The State of Humanities in Higher ...
National Endowment for the Humanities, Office of Publications
core
PHILOSOPHY AND THE STUDY OF GLOCALIZATION
Glocalism: Journal of Culture, Politics and InnovationWithin the bosom of the humanities philosophy reposes and, as an academic field, it is ever so often criticized for its aloofness. In a recent book, Roudometof and Dessi (2022, 9-10) politely quip that philosophy’s engagement with the “glocal” has been ...
ODYSSEUS MAKRIDIS
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source