Results 121 to 130 of about 1,461,417 (388)
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
The University, Neoliberalism, and the Humanities: A History
Humanities, 2017 Neoliberalism has since the 1970s had a significant negative impact on higher education in the U.S., but this ideology and political program is not solely to blame for the current situation of the humanities or the university. The American university was
David R. Shumway
doaj +1 more source
Open Access – What’s New in the Arts & Humanities?
, 2015 Learn about some of the newest open access publications and platforms designed to support the open sharing of humanities research. Join a discussion with librarian liaisons to arts and humanities departments about how Gettysburg faculty and the library ...
Scholarly Communications,
core
Spanish lecturers’ beliefs about English medium instruction: STEM versus Humanities
International Journal of Bilingual Education and Bilingualism, 2019 More and more European universities are implementing English Medium Instruction (EMI) programs, but such policies tend to be top-down and pay insufficient attention to contextual factors such as the degree of internationalization of the universities ...
Hanne Roothooft
semanticscholar +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Claiming expertise from betwixt and between: Digital humanities librarians, emotional labor, and genre theory [PDF]
, 2017 Librarians\u27 liminal (intermediate) position within academia situates us to make unique contributions to digital humanities (DH). In this article, we use genre theory, feminist theory, and theories of emotional labor to explore the importance of ...
Logsdon, Alexis +2 more
core +2 more sources
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
China and the Humanities: At the Crossroads of the Human and the Humane [PDF]
, 2013 This contains the sections of this volume produced by the editor, including the front matter, Preface, Introduction and Index.
openaire +2 more sources
Politeness in Machine-Human and Human-Human Interaction
Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 2016 Computers communicate with humans in ways that increasingly resemble interactions between humans. Nuances in expression and responses to human behavior become more sophisticated, and they approach those of human-human interaction. The question arises whether we want systems eventually to behave like humans, or whether systems should, even when much ...
Meyer, Joachim +4 more
openaire +5 more sources
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source