Results 101 to 110 of about 1,090,985 (351)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
State opinio juris and international humanitarian law pluralism [PDF]
, 2015 International humanitarian law has developed through a pluralistic process. Its history reveals a pattern of rough proportionality between State opinio juris and non-State expressions of law.
Schmitt, Michael N., Watts, Sean
core +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Technological Singularity [PDF]
, 2017 Hypothetically, technological singularity is considered as irreversible changes to the mankind resulted from technological growth due to the invention of artificial super intelligence (AI). The major concern is that AI will come out of the control and,
Garzha, N.S. +3 more
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Towards a politics for human rights: Ambiguous humanity and democratizing rights [PDF]
, 2013 Human rights are a suspect project – this seems the only sensible starting point today. This suspicion, however, is not absolute and the desire to preserve and reform human rights persists for many of us.
Hoover, J.
core +1 more source
FEBS Letters, EarlyView.This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk +3 more
wiley +1 more source
Psychological Topics, 2012 The prevalence of individuals using social networking sites to stay connected has increased considerably in only a few years and the information posted is now being used by organizations for employee selection.
Kerry Newness +2 more
doaj
Ambivalence or Melancholia: The Ontogenesis of Religious Sentiment
ReligionsThe psychoanalytic explanation of religious sentiment is genetic, meaning that it probes the psychological processes behind the formation of such sentiment. Freud ascribed the genesis of religious sentiment to human infantile helplessness and ambivalence
Chuansong Huo, Fei Ju
doaj +1 more source
Species of Compassion: Aesthetics, Anaesthetics, and Pain in the Physiological Laboratory
19, 2012 This essay explores the interplay of different species of compassion with regard to physiological practices in the final decades of the nineteenth century.
Rob Boddice
doaj +2 more sources