Results 81 to 90 of about 957,320 (315)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Epidemic Response and Reflections on the 1918—1919 Influenza Pandemic in Shanghai
Yixue yu zhexueShanghai, as one of the first cities in China to undergo modernization, was severely affected by the 1918—1919 influenza pandemic, experiencing three waves of the epidemic in the summer of 1918, the autumn of 1918, and the spring of 1919.
Hongyu CHEN, Yuan YUAN
doaj +1 more source
Water purification using porous ceramics prepared by recycling volcanic ash and waste glass
Applied Water Science, 2017 Water purification was examined using porous ceramics prepared by sintering a powder mixture of volcanic ash, waste glass and a small amount of wood charcoal.
Tomohiro Ando +4 more
doaj +1 more source
The Dignity and Humanity of Bruce Springsteen\u27s Criminals [PDF]
, 2005 In this essay, I discuss Springsteen\u27s criminals by focusing on two albums, Nebraska and The Ghost of Tom Joad, and Springsteen\u27s title song to the movie soundtrack Dead Man Walking. These are classic albums about criminals and prisoners, and Dead
Smith, Abbe
core +1 more source
Emergence of wellbeing in community participation [PDF]
, 2014 This paper explores and reflects upon the literature and several mini case studies to recommend a change of focus for the linking management and development of community participants and community organisations.
George, Karen, Sice, Petia
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in EndocrinologyAimTo explore the association of evidence-based cardiovascular preventive therapies with cardiovascular and renal outcomes in type 2 diabetes (T2DM) patients with established or high risk of atherosclerotic cardiovascular disease (ASCVD).MethodsIn this ...
Jian-Qing Tian +5 more
doaj +1 more source
Journal of biomedical discovery and collaboration, 2006 Scientific and popular lore have promulgated a connection between emotion and the limbic forebrain. However, there are a variety of structures that are considered limbic, and disagreement as to what is meant by "emotion". This essay traces the initial studies upon which the connection between emotion and the limbic forebrain was based and how ...
openaire +2 more sources