Results 171 to 180 of about 95,544 (345)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Psychodiagnostics and Differentiated Approach Criteria in Penitentiary Psychology [PDF]

Пенитенциарная наука
Introduction: the problem of identifying aggressiveness and criminal inclinations remains relevant in modern penitentiary science. Many psychologists have been using psychological diagnostic methods for many years, however, the number of works in the ...
LYUDMILA N. SOBCHIK
doaj  

Large‐cohort humanized NPI mice reconstituted with CD34 ⁺ hematopoietic stem cells are feasible for evaluating preclinical cancer immunotherapy [PDF]

, 2022
Xiongfei Xu, Haihui Gu, Hongwei Li, Suizhi Gao, Xiaohan Shi, Jing Shen, Bo Li, Huan Wang, Kailian Zheng, Zhuo Shao, Peng Cheng, Zhanshan Cha, Siying Peng, Yongzhan Nie, Zhaoshen Li, Shiwei Guo, Baohua Qian, Gang Jin   +17 more
openalex   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Pharmacokinetic‐pharmacodynamic modelling of risankizumab using chronic plaque psoriasis real‐world data

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Risankizumab is a high‐cost biologic treatment for chronic plaque psoriasis, an immune‐mediated inflammatory disease presenting with painful red scaly skin lesions. Inter‐individual heterogeneity in treatment response may be better addressed with personalised rather than fixed dosing. We sought to develop a pharmacokinetic/pharmacodynamic (
Charlotte M. Thomas, Jessica Ruoheng Wei, David Baudry, Zehra Arkir, Bola Coker, Tejus Dasandi, Kingsley Powell, Monica Arenas‐Hernandez, Jenny Leung, Krystal Rawstron, Chioma Nwaogu, Richard Woolf, Andrew E. Pink, Jonathan Barker, Joseph F. Standing, Catherine H. Smith, Satveer K. Mahil   +16 more
wiley   +1 more source

Humanization of Care: Key Elements Identified by Patients, Caregivers, and Healthcare Providers. A Systematic Review

Patient, 2019
I. Busch, F. Moretti, Giulia Travaini, A. Wu, M. Rimondini   +4 more
semanticscholar   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Introduction: Humanizing Studies of Refuge and Displacement?

Refuge, 2021
Hanno Brankamp, Yolanda Weima
doaj   +1 more source

HUMANIZACIÓN DEL CUIDADO DE ENFERMERÍA DURANTE EL PARTO HUMANIZATION IN THE INFIRMARY’S CARE TAKE DURING CHILDBIRTH

Revista U.D.C.A Actualidad & Divulgación Científica, 2008
RESUMEN A lo largo de la trayectoria profesional en diferentes instituciones de salud y durante la experiencia de estar en contacto con las mujeres en trabajo de parto, se han reportado quejas de maltrato por parte del personal de salud.
Rosa Coral Ibarra
doaj  

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source