Results 101 to 110 of about 1,667 (307)

Monitoring of imatinib targeted delivery in human leukocytes

European Journal of Pharmaceutical Sciences, 2013
The success of imatinib therapy in chronic myeloid leukemia is highly influenced by its active transport into target cells. However, the methodology for analytical evaluation of intracellular drug concentration is rare and usually reliant upon the use of radioactively labeled drugs.
Eva, Kralj, Simon, Žakelj, Jurij, Trontelj, Tadej, Pajič, Irena, Preložnik Zupan, Peter, Černelč, Barbara, Ostanek, Janja, Marc, Albin, Kristl   +8 more
openaire   +2 more sources

Importância da realização do plano de parto na saúde materno infantil [PDF]

, 2022
Objetivo: Identificar e descrever as evidências científicas disponíveis na literatura nacional e internacional sobre a importância da realização do plano de parto na saúde materno-infantil.
Moura, Francyely dos Santos
core  

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

Advanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah, Muhammad Zulqarnain Zeb, Muhammad Husnain Zeb, Babar Shabbir   +3 more
wiley   +1 more source

Biomaterials for Drug Delivery and Human Applications

Materials
Biomaterials embody a groundbreaking paradigm shift in the field of drug delivery and human applications. Their versatility and adaptability have not only enriched therapeutic outcomes but also significantly reduced the burden of adverse effects. This work serves as a comprehensive overview of biomaterials, with a particular emphasis on their pivotal ...
openaire   +3 more sources

B/ordering and healthcare access for migrants with precarious status: The role of healthcare workers in counteracting restrictive policies

American Journal of Community Psychology, EarlyView.
Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné, Jill Hanley, Élise Bourgeois‐Guérin, Pénélope Boudreault   +3 more
wiley   +1 more source

Participação dos pais no nascimento em maternidade pública: dificuldades institucionais e motivações dos casais

Cadernos de Saúde Pública
A participação dos pais no nascimento, presente na humanização da assistência ao parto, afina-se com o crescente envolvimento dos homens nos cuidados com as crianças.
Maria Luiza Mello de Carvalho
doaj  

Humanized extracellular vesicles for efficient RNA delivery

Proceedings of the National Academy of Sciences
Engineered extracellular vesicles (EVs) are a class of nonviral delivery vectors for RNA-based vaccines and gene therapies. A specialized form of engineered EVs, known as enveloped protein nanocages (EPNs), has been developed to enhance cargo loading and delivery.
Xiang Ma, Sophia R. Zhao, Constance L. Cepko   +2 more
openaire   +2 more sources

Building Community Amidst the Institutional Whiteness of Graduate Study: Black Joy and Maroon Moves in an Academic Marronage

Australian Journal of Social Issues, EarlyView.
ABSTRACT This article reflects on the construction of a supportive community of Black Afro‐diasporic graduate students and their supervisors researching issues relating to race in the field of education in Australia. It draws on the concept of marronage—a term rooted in the fugitive act of becoming a maroon, where enslaved people enacted an escape in ...
Hellen Magoi, Casianus Gemoh, Denise Chapman, Edmund Hypolite, Simon Angok, Melanie Baak, Joel Windle   +6 more
wiley   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

The effect of educational technology use to guide parturient women's companions: a randomized controlled study

Revista da Escola de Enfermagem da USP
Objective: To evaluate the companion's role during the labor and delivery processes, comparing the influence of the use of an educational technology.
Laise Ramos e Silva, Camila Teixeira Moreira Vasconcelos, Ana Izabel de Oliveira Nicolau, Liana Mara Rocha Teles, Gabriela Lima Ribeiro, Ana Kelve de Castro Damasceno   +5 more
doaj   +2 more sources