Results 111 to 120 of about 1,306,169 (311)

Auto Delivery Moving Company (1911)

open access: yes, 1911
Best furniture and piano moving equipment in the city. All work done by auto, insuring quicker and safer delivery. Our auto service insures prompt delivery of trunks and baggage.Automobiles, carriages and wagons Commercial and professional services ...
Auto Delivery Company
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Drug delivery with living cells [PDF]

open access: yes, 2016
The field of drug delivery has grown tremendously in the past few decades by developing a wide range of advanced drug delivery systems. An interesting category is cell-based drug delivery, which includes encapsulation of drugs inside cells or attached to
Fliervoet, Lies A L   +1 more
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Engineered Transformer Base Editor with Enhanced Editing Efficiency

open access: yesAdvanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen   +5 more
wiley   +1 more source

Humanizing factors for hotel online booking [PDF]

open access: yes, 2020
Humanizing should be implemented for making online booking more suitable for people and make it works in more humane manner. Currently, online booking system faced many problems such as difficulty to interpret the customer satisfaction, lack of ...
Azmi, Lina Fatini
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Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

open access: yes, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R   +3 more
core   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu   +4 more
wiley   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

open access: yesAdvanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen   +11 more
wiley   +1 more source

The effect of educational technology use to guide parturient women's companions: a randomized controlled study

open access: yesRevista da Escola de Enfermagem da USP
Objective: To evaluate the companion's role during the labor and delivery processes, comparing the influence of the use of an educational technology.
Laise Ramos e Silva   +5 more
doaj   +2 more sources

Proceedings of the Second Conference on Veterans in Society: Humanizing the Discourse

open access: yes, 2015
The second conference on Veterans in Society represented ongoing growth and continuity in our research program. Our first conference, “Changing the Discourse” (2013), marked the first academic conference solely focused on veteran-related research and ...

core  

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang   +17 more
wiley   +1 more source

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