Results 191 to 200 of about 1,667 (307)

Drug delivery into the human brain

open access: yes, 2015
Large proteins for the treatment of diseases such as Parkinson s, Alzheimer s and other disorders affecting the central nervous system (CNS) cannot easily penetrate the brain blood barrier (BBB). As an alternative to delivery through the blood stream, drugs may be inserted into the brain tissue directly using invasive release techniques.
openaire   +1 more source

Startups Driving Artificial Intelligence Into Clinical Dermatology

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transitioning from innovation to routine clinical application in dermatology. This review examines how AI‐enabled technologies are being developed and integrated across diverse clinical purposes and workflows.
Dominique Du Crest   +10 more
wiley   +1 more source

Visual Implied Motion in Marketing: A Dual‐Route Framework of Perceptual Persuasion

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT Depicting movement in static marketing stimuli, referred to as ‘implied motion’, is widely used across packaging, logos, and advertising, and multimodal brand communications. Despite growing evidence of its persuasive impact, the underlying psychological mechanisms and boundary conditions remain theoretically fragmented. This systematic review
Tianyi Zhang, Charles Spence
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Editorial: Distributed training and rural health professions education. [PDF]

open access: yesFront Med (Lausanne)
Strasser RP   +4 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

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