Results 61 to 70 of about 1,827,826 (348)
Glycosylation of glycolipids in cancer: basis for development of novel therapeutic approaches [PDF]
, 2013 Altered networks of gene regulation underlie many pathologies, including cancer. There are several proteins in cancer cells that are turned either on or off, which dramatically alters the metabolism and the overall activity of the cell, with the complex ...
Daniotti, Jose Luis +4 more
core +2 more sources
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Revista de Enfermagem Referência, 2010 A hospitalização de todas as parturientes, em nome da segurança e bem-estar da mãe e bebê, introduziu uma assistência mecânica, impessoal e intervencionista no parto, fazendo ressurgir o parto em domicílio.
Priscila Maria Colacioppo +4 more
doaj
SEPARATION OF THE WOMAN AND HER COMPANION DURING CESAREAN SECTION: A VIOLATION OF THEIR RIGHTS
Cogitare Enfermagem, 2018 Objective: to reveal the experience of the woman and her companion whose right to share the birth of their child was violated. Method: qualitative, exploratory-descriptive research.
Adaiana Fátima Almeida +3 more
doaj +1 more source
Style, Narrative, and Cultural Politics in Bullitt [PDF]
, 2017 Peter Yates’s 1968 film Bullitt cemented the reputation of its star, Steve McQueen, as “the essence of cool” – to borrow a phrase from the title of the 2005 documentary that reflects on the star’s legacy. As the film reveals, however, and the documentary
Childs, Jeffrey Scott
core
Advanced Science, EarlyView.AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li +6 more
wiley +1 more source
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Reaching Out to Tribal Communities: Lessons Learned and Approaches to Consider [PDF]
, 2019 When transportation safety decision-making is desired, the involvement and engagement with a community is essential. A streamlined delivery of a project or program is more likely to occur when active dialogue and an exchange of ideas occurs in advance ...
Awwad-Rafferty, Rula +2 more
core
Realistic Man, Fantasy Policeman: The Longevity of Ruth Rendell's Reginald Wexford [PDF]
, 2016 Publisher does not allow open access until after ...
Schnabel, Jennifer
core +1 more source
Human peripheral blood‑derived exosomes for microRNA delivery
International Journal of Molecular Medicine, 2019 Exosomes serve important functions in cell‑to‑cell communication and biological functions by serving as a delivery cargo shuttle for various molecules. The application of an improved delivery method for microRNAs (miRNAs/miRs) may enhance their potential as a therapeutic tool in cardiac diseases.
Kang, Ji-Young +6 more
openaire +4 more sources