Results 71 to 80 of about 1,827,826 (348)
Advanced Science, EarlyView.Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
O PARTO HUMANIZADO E O SEU IMPACTO NA ASSISTÊNCIA A SAÚDE
Revista Educação em Saúde, 2015 Objective: Analysis over the humanized process of birth and it’s vicissitudes that approach both physiological and psychosocial aspects and also the technochratic specifications of it’s operation.
Laiane Pereira Barros +5 more
doaj
Saúde em DebateRESUMO Este artigo analisa a percepção dos profissionais de saúde da maior maternidade do estado da Paraíba acerca da inserção das doulas no processo de cuidado. Trata-se de estudo qualitativo, com 24 profissionais de saúde, cujo instrumento de coleta de
Thuany Bento Herculano +3 more
doaj +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Childbirth and birth assistance: a quantitative study
Online Brazilian Journal of Nursing, 2007 This research, of quantitative nature, aimed to characterize the assistance offered to the binomial mother-baby in the childbirth and birth and to discuss if this assistance minimizes the risks to maternal and newborn health.
Sonia Mara Faria Simões +2 more
doaj
O SIGNIFICADO DO CUIDADO AO PARTO NA VOZ DE QUEM CUIDA: UMA PERSPECTIVA À LUZ DA HUMANIZAÇÃO
Cogitare Enfermagem, 2009 Objetivamos analisar o significado do cuidado ao parto por enfermeiras que atuam em sala de parto. O estudo qualitativo foi realizado em uma maternidade pública federal na cidade de Fortaleza-CE, no mês de abril de 2007, através de entrevista ...
Karla de Abreu Peixoto Moreira +5 more
doaj +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Advanced Science, EarlyView.Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
The poetic is political….and other notes on engaged scholarship [PDF]
, 2009 Instrumental and objectivist logics maintain a hegemonic place in Western scholarship, reasoning skills powerfully equipped to address certain dilemmas even as they may obscure other ways of knowing.
Dutta, Mohan J. +3 more
core +1 more source
Enablers and Barriers to Implementing ICU Follow-Up Clinics and Peer Support Groups Following Critical Illness: The Thrive Collaboratives [PDF]
, 2019 OBJECTIVES: Data are lacking regarding implementation of novel strategies such as follow-up clinics and peer support groups, to reduce the burden of postintensive care syndrome.
Aparanji, Krishna +35 more
core +2 more sources
Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer
Advanced Science, EarlyView.Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen +13 more
wiley +1 more source