Results 141 to 150 of about 19,747,875 (398)

Acclimatization to cold in humans [PDF]

This review focuses on the responses and mechanisms of both natural and artificial acclimatization to a cold environment in mammals, with specific reference to human beings.
Greenleaf, John E., Kaciuba-Uscilko, Hanna   +1 more
core   +1 more source

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver [PDF]

, 2002
Stephan R. Vavricka, Jessica van Montfoort, Huy Riêm Ha, Peter J. Meier, Karin Fattinger   +4 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Short-Wavelength Light Sensitivity of Circadian, Pupillary, and Visual Awareness in Humans Lacking an Outer Retina [PDF]

, 2007
F H Zaidi, Joseph T. Hull, Stuart N. Peirson, Katharina Wulff, Daniel Aeschbach, Joshua J. Gooley, George C. Brainard, Kevin Gregory-Evans, Joseph F. Rizzo, Charles A. Czeisler, F. Foster, Merrick J. Moseley, Steven W. Lockley   +12 more
openalex   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells [PDF]

, 2015
Tovah Wolf, Scott Baier, Janos Zempleni
openalex   +1 more source

Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.

Molecular biology and evolution, 1993
Kazuko Tamura, M. Nei
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Human Cortical Brain and Biomechanical Responses to Abrupt Changes in Exoskeleton Assistance While Walking

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Robotic exoskeletons have advanced significantly, yet control systems still face challenges in delivering assistance that seamlessly aligns with the user’s musculoskeletal system.
Seongmi Song, Courtney A. Haynes, J. Cortney Bradford   +2 more
doaj   +1 more source