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Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Who are we? The question of human nature seems to haunt all disciplines. That may tell us how very “human” the question is. Answers vary widely. Yet scientists—anthropologists, geneticists, ethologists, and developmental and evolutionary biologists—rely on observations and empirical data. Their conclusions thus seem more objective. Biologically, humans
openaire +2 more sources
Humanitarianism, humanity, human [PDF]
(2003). Humanitarianism, humanity, human. Journal of Human Rights: Vol. 2, No. 2, pp. 253-258.
openaire +2 more sources
Similarity or Difference as a Basis for Justice: Must Animals Be Like Humans to Be Legally Protected from Humans? [PDF]
Justice may not require that animals be exactly the same as humans or that they have rights exactly coterminous with the rights of humans, but justice would require that animals receive protection in ways that match up with those similarities they share ...
Bryant, Taimie L.
core +1 more source
Primordial follicular assembly in humans : revisited [PDF]
Peer ...
A. Maheshwari+8 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Human to human transmission of H7N9 [PDF]
Since the new avian influenza virus, H7N9, first emerged in China, a primary concern has been whether it might spread between humans. The vast majority of the 133 confirmed cases reported so far seem to be epidemiologically unconnected, with many patients reporting a recent history of exposure to live poultry, which are suspected to be a main reservoir
James W. Rudge+2 more
openaire +2 more sources
Olfactory Conditioning of Positive Performance in Humans [PDF]
Olfactory conditioning effects have been widely demonstrated in the animal literature but more seldom in human populations and rarely of consciously controlled human behaviors.
Chu, Simon
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source