Humidifier disinfectant, sodium dichloroisocyanurate (NaDCC): assessment of respiratory effects to protect workers’ health [PDF]
Scientific Reports, 2021 In South Korea, it has been found that biocides used to control and eliminate harmful organisms are used as humidifier disinfectants and cause lung disease in users.
DongSeok Seo, Yong-Hoon Lee, JiMin Jo
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Mental health impact on a humidifier disinfectant disaster victim: a case report. [PDF]
Ann Occup Environ Med, 2020 In Korea, the cause of lung disease of unknown origin was identified as humidifier disinfectants in November 2011. In February 2017, the 'Special Act on Remedy for Damage Caused by Humidifier Disinfectants' was promulgated. Even though emotional and mental injuries caused by humidifier disinfectants have been reported, the focus of the special act has ...
Lee YS +5 more
europepmc +4 more sources
Major concerns regarding lung injury and related health conditions caused by the use of humidifier disinfectant [PDF]
Environmental Health and Toxicology, 2016 A total of 221 patients were evaluated to be humidifier disinfectant associated with lung injury (HDLI) through two rounds of programs through April 2015. The humidifier disinfectant (HD) brands most often associated with HDLI were found to be Oxy (n=151,
Donguk Park
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NOTCH1 Pathway is Involved in Polyhexamethylene Guanidine-Induced Humidifier Disinfectant Lung Injuries. [PDF]
Yonsei Med J, 2020 An outbreak of fatal humidifier disinfectant lung injuries (HDLI) occurred in Korea. Human studies on mechanisms underlying HDLI have yet to be conducted. This study aimed to investigate methylation changes and their potential role in HDLI after exposure to HDs containing polyhexamethylene guanidine-phosphate.
Lee E +11 more
europepmc +4 more sources
Integrated evidence supports a causal association between PHMG-P exposure and pneumonitis [PDF]
Epidemiology and HealthPolyhexamethylene guanidine phosphate (PHMG-P) is a guanidine-based disinfectant previously used in household humidifiers in Korea. This study evaluated whether PHMG-P exposure is causally linked to pneumonitis by integrating epidemiological ...
Yong Joo Park +8 more
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Kathon Induces Fibrotic Inflammation in Lungs: The First Animal Study Revealing a Causal Relationship between Humidifier Disinfectant Exposure and Eosinophil and Th2-Mediated Fibrosis Induction [PDF]
Molecules, 2020 Currently available toxicity data on humidifier disinfectants are primarily limited to polyhexamethylene guanidine phosphate-induced lung fibrosis.
Mi-Kyung Song, Dong Im Kim, Kyuhong Lee
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Humidifier Disinfectant-Associated Lung Injury: Six Years after the Tragic Event. [PDF]
Tuberc Respir Dis (Seoul), 2017 In 2011, a cluster of peripartum patients were admitted to the intensive care unit of a tertiary hospital in Seoul with signs and symptoms of severe respiratory distress of unknown etiology. Subsequent epidemiological and animal studies suggested that humidifier disinfectant (HD) might represent the source of this pathology.
Kim WY, Hong SB.
europepmc +3 more sources
Humidifier disinfectant disaster: what is known and what needs to be clarified [PDF]
Environmental Health and Toxicology, 2016 Objectives After the initial investigations by the Korea Centers for Disease Control in 2011, over 1000 suspicious cases of humidifier disinfectant (HD) victims were subsequently reported by 2015, and numbers are still increasing dramatically in 2016 in ...
Sungkyoon Kim, Domyung Paek
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Evaluation report on the causal association between humidifier disinfectants and lung injury [PDF]
Epidemiology and Health, 2016 OBJECTIVES: As of November 2011, the Korean government recalled and banned humidifier disinfectants (HDs) from the market, because four case-control studies and one retrospective epidemiological study proved the association between HDs and lung injury of
Cheong, HK +6 more
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Humidifier disinfectant: 78 deaths and still in progress.
Iranian Journal of Public Health, 2013 Yong Han Kim
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