Results 131 to 140 of about 17,046 (244)

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

It Was Possible to Reduce the Pain of the Victims of Humidifier Disinfectant

Journal of Environmental Health Sciences, 2022
Pangyi Kim, Yoon-Hyeong Choi, YeongChul Park, Tae-Hyun Park, JongHan Leem   +4 more
openaire   +2 more sources

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Humidifier

, 2020
Předmětem bakalářské práce je návrh designérského řešení pro zvlhčovací zařízení. Cílem bylo navrhnout takový univerzální zvlhčovač, který by mohl být použit jak v soukromém bytu tak i ve veřejném prostoru. Z pohledu estetiky jsem vybrala cestu směrující
Anastasiya Asayonak
core  

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Identifikasi Mikroorganisme Patogen pada Air dalam Tabung Humidifier Inkubator di NICU RSUP Dr. M. Djamil Padang [PDF]

, 2018
MICROORGANISM IDENTIFICATION IN THE WATER OF INCUBATOR HUMIDIFIER TUBE AT NICU OF DR. M. DJAMIL HOSPITAL PADANG By Amalia Savira ABSTRACT Water content in incubator humidifier tube that create the moist air for neonatus-on-risk are being ...
Amalia, Savira
core   +1 more source

Review on Safety and Health Information on Humidifier Disinfectant [PDF]

Korean Journal of Environmental Health Sciences, 2017
Dong-Uk Park, Seunghee Lee, Heung-Kyu Lim, Seo-Youn Bae, Seung-Hun Ryu, Jong-Ju Ahn   +5 more
openaire   +1 more source

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

Advanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu, Yufan Xie, Lanxin Wang, Luyan Ma, Xiaofei Ge, Jiawei Wang   +5 more
wiley   +1 more source

EC5 Disinfection and Disinfectants [PDF]

, 1922
This extension circular 5 titled Disinfection and Disinfectants is a description of all kinds of disinfectants and their ...
Skidmore, L. V.
core