Results 141 to 150 of about 1,064 (256)
Advanced Science, EarlyView.The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang +9 more
wiley +1 more source
INACTIVATION KINETICS OF \u3ci\u3eBOTRYTIS CINEREA\u3c/i\u3e INOCULATED ON STAINLESS STEEL COUPONS BY CHLORINE DIOXIDE GAS [PDF]
, 2019 Botrytis cinerea (B. cinerea) is a soil borne fungus that produces airborne spores and causes serious damage to crops. Inactivation of B. cinerea has become a difficult challenge as it has become more resistant to fungicides, disinfectants, thermal, and ...
Dhanapal, Aruna
core +1 more source
A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation
Advanced Science, EarlyView.A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu +7 more
wiley +1 more source
가습기살균제 피해 사건에 대한 언론 보도 분석 연구: 3개 일간지 기사를 중심으로 [PDF]
, 2017 학위논문 (석사)-- 서울대학교 대학원 : 행정학과(정책학전공), 2017. 2. 우지숙.본 연구는 2011년 첫 피해자가 발생한 이후 2016년 검찰의 사건 수사 재개 과정을 통해 재점화된 이슈인 가습기살균제 피해 사건에 대하여 집중 보도한 국내 주요 일간지 3사의 언론 보도에 대해 분석하였다.
김현미
core
Advanced Science, EarlyView.ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao +12 more
wiley +1 more source
Advanced Science, EarlyView.Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao +12 more
wiley +1 more source
Advanced Science, EarlyView.This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang +21 more
wiley +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Integrative multi‐omics approach for mechanism of humidifier disinfectant‐associated lung injury [PDF]
Clinical and Translational Medicine, 2021 Jeong‐Hyun Kim +14 more
openaire +3 more sources