Inhalation Toxicity of Humidifier Disinfectants as a Risk Factor of Children’s Interstitial Lung Disease in Korea: A Case-Control Study [PDF]
PLoS ONE, 2013 BACKGROUND: The occurrence of numerous cases of interstitial lung disease in children (chILD) every spring in Korea starting in 2006 raised suspicion about a causal relationship with the use of humidifier disinfectants (HDs). The aim of this study was to
Ju-Hee Seo, Hyung Young Kim, Jinho Yu
exaly +9 more sources
Evidence integration on health damage for humidifier disinfectant exposure and legal presumption of causation [PDF]
Epidemiology and Health, 2023 OBJECTIVES Inhalation exposure to humidifier disinfectants has resulted to various types of health damages in Korea. To determine the epidemiological correlation necessary for presuming the legal causation, we aimed to develop a method to synthesize the ...
Mina Ha +10 more
doaj +3 more sources
Mitochondria disease due to humidifier disinfectants: diagnostic criteria and its evidences [PDF]
Environmental Analysis, Health and Toxicology, 2020 Humidifier disinfectant damages caused by the misuse of humidifier disinfects, such as polyhexamethylene guanidine (PHMG), resulted in chemical disasters in South Korea in 2011. About four million people were exposed to humidifier disinfectants (HDs) in the 17 years between 1994 and 2011.
Hwan-Cheol Kim, Jong Han Leem
exaly +5 more sources
Toxicological evidence integration to confirm the biological plausibility of the association between humidifier disinfectant exposure and respiratory diseases using the AEP-AOP framework [PDF]
Epidemiology and HealthOBJECTIVES Exposure to humidifier disinfectants has been linked to respiratory diseases, including interstitial lung disease, asthma, and pneumonia. Consequently, numerous toxicological studies have explored respiratory damage as both a necessary and ...
Ha Ryong Kim +10 more
doaj +3 more sources
Characterizing Subjects Exposed to Humidifier Disinfectants Using Computed-Tomography-Based Latent Traits: A Deep Learning Approach [PDF]
International Journal of Environmental Research and Public Health, 2022 Around nine million people have been exposed to toxic humidifier disinfectants (HDs) in Korea. HD exposure may lead to HD-associated lung injuries (HDLI).
Hongseok Ko +2 more
exaly +3 more sources
Exposure to Humidifier Disinfectants Increases the Risk for Asthma in Children [PDF]
American Journal of Respiratory and Critical Care Medicine, 2018 Seung-Hwa Lee +2 more
exaly +5 more sources
Comparison of maternal and neonatal survival exposed to humidifier disinfectants during perinatal periods: a case-series study [PDF]
Scientific Reports, 2023 A humidifier disinfectant (HD) has been prohibited by the government due to its serious effects on the human body. Several studies on the relationship between HD and lung diseases have been performed independently on children and adults.
Jang Hoon Lee +2 more
doaj +2 more sources
Humidifier Disinfectant–associated Children’s Interstitial Lung Disease
American Journal of Respiratory and Critical Care Medicine, 2014 Abstract Rationale Beginning in 2006, epidemics of a fatal lung injury of unknown cause in children were observed in Korea every spring. A recent study demonstrated that this type of children’s interstitial lung disease (chILD) is associated with humidifier disinfectant use.
Kyung Won, Kim +33 more
core +6 more sources
Inhalation Lung Injury Associated with Humidifier Disinfectants in Adults. [PDF]
J Korean Med Sci, 2016 We recently established a novel disease entity presented as progressive respiratory failure associated with the inhalation of humidifier disinfectants. In April 2011, we encountered a series of peripartum patients with complaints of respiratory distress of unknown etiology, which was an uncommon phenomenon.
Huh JW +9 more
europepmc +3 more sources
The Humidifier Disinfectant Disaster in Korea: Implications for Preventive Medicine and Public Health [PDF]
Journal of Preventive Medicine and Public HealthThe humidifier disinfectant disaster in Korea was one of the most severe environmental health disasters of recent decades. It showed that indoor household chemical products used in daily life can cause fatal health effects at the population level when ...
Sue K. Park +5 more
doaj +2 more sources