The past, present and future of humidifier disinfectant-associated interstitial lung diseases in children [PDF]
Exposure to environmental factors can cause interstitial lung diseases (ILDs); however, such types of ILDs are rare. From 2007 to 2011, an ILD epidemic occurred in South Korea owing to inhalational exposure to toxic chemicals in humidifier disinfectants (
Eun Lee, So-Yeon Lee, Soo-Jong Hong
doaj +4 more sources
Humidifier Disinfectants Are a Cause of Lung Injury among Adults in South Korea: A Community-Based Case-Control Study. [PDF]
An outbreak of lung injury among South Korean adults was examined in a hospital-based case-control study, and the suspected cause was exposure to humidifier disinfectant (HD).
Ji-Hyuk Park +12 more
doaj +2 more sources
Exposures to humidifier disinfectant and various health conditions in Korean based on personal exposure assessment data of claimants for compensation [PDF]
Background Humidifier disinfectants (HDs) were commonly used household chemicals to prevent microbial growth in a humidifier water tank in South Korea.
Myeongjin Hong +8 more
doaj +2 more sources
Risk of non-cancer respiratory diseases attributed to humidifier disinfectant exposure in Koreans: age-period-cohort and differences-in-difference analyses [PDF]
OBJECTIVES Humidifier disinfectants (HDs) were sold in Korea from 1994 until their recall in 2011. We examined the incidence patterns of 8 respiratory diseases before and after the HD recall and estimated the attributable risk in the Korean population ...
Jaiyong Kim +10 more
doaj +2 more sources
Association between humidifier disinfectant use duration and lung cancer development in Korea [PDF]
OBJECTIVES This study was conducted to assess the association between the duration of humidifier disinfectant use and lung cancer development. METHODS We analyzed data from 3,605 applicants registered for compensation from the Korean government due to ...
Sungchan Kang +10 more
doaj +2 more sources
Integrated evidence supports a causal association between PHMG-P exposure and pneumonitis [PDF]
Polyhexamethylene guanidine phosphate (PHMG-P) is a guanidine-based disinfectant previously used in household humidifiers in Korea. This study evaluated whether PHMG-P exposure is causally linked to pneumonitis by integrating epidemiological ...
Yong Joo Park +8 more
doaj +2 more sources
Use of Disinfectants and Cleaning Products Associated with Respiratory Disease: A Scoping Review [PDF]
Introduction: there is extensive evidence on the harmful respiratory effects of exposure to disinfectants and cleaning products. Methodology: an exploratory systematic review was carried out in five databases: LILACS, PubMed, MEDLINE and BIREME.
Paula Andrea García Quinto +4 more
doaj +2 more sources
Evaluation of 2-methyl-4-isothiazolin-3-one-induced human pulmonary toxicity using integrated air-liquid-interface and a lung-on-chip [PDF]
A 3:1 disinfectant composed of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazolin-3-one (MIT) has been widely used in water-based household products such as detergents, toothpaste, and cosmetic applications.
Sohyun Park +6 more
doaj +2 more sources
Polyhexamethylene guanidine phosphate exposure induces abnormal behaviors by disrupting synaptic formation and activity in the cerebral cortex [PDF]
Background Polyhexamethylene guanidine phosphate (PHMG-p), a commonly utilized ingredient in humidifier disinfectants, has emerged as a primary factor contributing to pulmonary damage, asthmatic conditions, and prenatal complications in South Korea ...
Moon Yi Ko +11 more
doaj +2 more sources
Following widespread use of humidifier disinfectants (HDs) in South Korea from the late 1990s until their recall in 2011, clusters of respiratory illnesses emerged.
Kyoung Sook Jeong, Jaiyong Kim
exaly +3 more sources

