Results 121 to 130 of about 811,080 (260)
Advanced Science, EarlyView.The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
Advanced Science, EarlyView.Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen +13 more
wiley +1 more source
Advanced Science, EarlyView.L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen +17 more
wiley +1 more source
The Difference Between Bacterial Growth in Humidifier and Non Humidifier at the Patient Who Got Oxygen Therapy [PDF]
, 2008 Introduction: Humidifier is a device for delivering oxygen to the patients. Before using it, the humidifier tube should fill with sterile water. There was a recent study that administering oxygen less than five liter per minutes, the tube was not load ...
Bakar, A. (Abu) +2 more
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Advanced Science, EarlyView.A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee +6 more
wiley +1 more source
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Newfoundland Lung Association Newsletter; Lung Association of Newfoundland and Labrador Newsletter
, 1982 The Northern Light, Summer 1982Contents Page -- The Cross of Lorraine or Double-Barred Cross -- Obituaries -- Editorial: 1982, A Year to Remember / E. G. House -- His Hon. W. Anthony Paddon, C.M. M.D.
Newfoundland Lung Association
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Scientific ReportsPolyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated associations between PHMG-p dose and lung ...
Sang Hoon Jeong +16 more
doaj +1 more source
Humidifier-Related Lung Injury Leading to Hypersensitivity Pneumonitis: A Case Report
CureusHumidifier lung is a subtype of hypersensitivity pneumonitis (HP) triggered by repeated exposure to an antigen. The mainstay of therapy is antigen avoidance. A Caucasian male in his 30s presented with a six-month history of progressively worsening dyspnea and cough. On presentation, he was hypoxic on room air.
Obregon, Mike, Faiek, Saif, White, Peter
openaire +2 more sources