Results 101 to 110 of about 3,474 (292)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Ventilator-associated pneumonia in patients using HME filters and heated humidifiers

, 2013
Ventilator-associated pneumonia (VAP) is a clinical form of hospital-associated pneumonia, which may develop within 48 h in patients on mechanical ventilation who had no pre-existing pneumonia at the time of intubation. The objective of this study was to
OĞUZ, SIDIKA
core   +1 more source

A Case of Healthcare Associated Pneumonia Caused by Chryseobacterium indologenes in an Immunocompetent Patient

Case Reports in Infectious Diseases, 2015
Chryseobacterium indologenes is nonmotile, oxidase, and indole positive Gram-negative aerobic bacilli which is widely found in plants, soil, foodstuffs, and water.
Salih Atakan Nemli, Tuna Demirdal, Serap Ural   +2 more
doaj   +1 more source

Predictors of indoor absolute humidity and estimated effects on influenza virus survival in grade schools

BMC Infectious Diseases, 2013
Background Low absolute humidity (AH) has been associated with increased influenza virus survival and transmissibility and the onset of seasonal influenza outbreaks.
Koep Tyler H, Enders Felicity T, Pierret Chris, Ekker Stephen C, Krageschmidt Dale, Neff Kevin L, Lipsitch Marc, Shaman Jeffrey, Huskins W Charles   +8 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

ANALISA PERANGKAT HUMIDIFIER PADA VENTILATOR

, 2023
This study aims to analyze humidifiers on ventilators for patients. Can find out the analysis of humidifiers on ventilators, explain, and apply knowledge about analysis of humidifiers on ventilators. In this study, quantitative descriptive research types
Priyulida, Fitria, Abdillah, Khairil, Sihotang, Anggi Tutamana, Ulina, Sri   +3 more
core  

Humidifier lung [PDF]

QJM: An International Journal of Medicine, 2019
Y, Tomoda, S, Murakami, K, Kawaguchi, T, Orihashi, K, Tanaka   +4 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Influence of ambient and ventilator output temperatures on performance of heated-wire humidifiers

, 2004
Although heated humidifiers are considered the most efficient humidification devices for mechanical ventilation, endotracheal tube occlusion caused by dry secretions has been reported with heated-wire humidifiers.
Maggiore, Salvatore Maurizio
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source