Results 61 to 70 of about 148,680 (286)

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis

Advanced Science, EarlyView.
Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan, Yuanyang Tan, Junhang Zhang, Xiaoya Liu, Jing Qu, Damien Chua, Hong Sheng Cheng, Joseph Han Sol Kim, Yu Xuan Liu, Changfei Qin, Yingzi Liu, Dezhi Li, Jikang Qiu, Mengshi Chi, Mingmin Bi, Qiwei Zhang, Yun Li, Masoumeh Motamedi Joibari, Stefan K Nilsson, Nguan Soon Tan, Yunping Fan, Liang Li   +21 more
wiley   +1 more source

Psychometric properties of the Brief-COPE for the evaluation of coping strategies in the Chilean population [PDF]

, 2018
The Brief-COPE is an abbreviated version of the COPE (Coping Orientation to Problems Experienced) Inventory, a self-report questionnaire developed to assess a broad range of coping responses. Currently, it is one of the best validated and most frequently
Alvear-Carrasco, Marcela, Barraza-Peña, Carmen Gloria, García, Felipe E., Reyes-Reyes, Alejandro, Wlodarczyk, Anna   +4 more
core   +4 more sources

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, EarlyView.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source

The Conceptualization, Measurement, and Role of Humor as a Character Strength in Positive Psychology

Europe's Journal of Psychology, 2014
In positive psychology, humor has been identified as one of 24 character strengths considered ubiquitously important for human flourishing. Unlike the other strengths, humor was a late addition to this classification system and its status as a strength ...
Kim R. Edwards, Rod A. Martin
doaj   +1 more source

Seven decades after Hans Asperger's observations: A comprehensive study of humor in individuals with Autism Spectrum Disorders [PDF]

, 2017
The aim of the present study was to better understand humor in individuals with Asperger's syndrome. Therefore, various humor and laughter related phenomena were investigated by means of various standardized humor instruments.
Huber, Oswald, Ruch, Willibald, Samson, Andrea C.   +2 more
core  

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

Advanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li, Jiaqi Fan, Tao Sun, Wushi Cui, Jiaxuan Zou, Weinan Yang, Liang Chen, Jian Xiao, Shicheng Wang, Tao Zhang, Jianqiao Hong, An Liu, Haobo Wu   +12 more
wiley   +1 more source

Music History- Laugh and Learn [PDF]

, 2019
The project I have chosen aligns with my curriculum project and research. Data will be gathered on the effects of laughter in the classroom. This research will show that humor can motivate students as well as aide memory.
Fagan, Jessica Ellen
core   +1 more source

Self-Pity: Exploring the Links to Personality, Control Beliefs, and Anger [PDF]

, 2003
Self-pity is a frequent response to stressful events. So far, however, empirical research has paid only scant attention to this subject. The present article aims at exploring personality characteristics associated with individual differences in feeling ...
Ainsworth, Ainsworth, Baltes, Beck, Becker, Block, Borg, Borkenau, Broderick, Brosschot, Byrne, Carmines, Carver, Charmaz, Costa, Costa, Costa, Costa, DiTommaso, Elson, Eysenck, Eysenck, Funder, Grunert, Grunert, Janke, John, Kahn, Krampen, Krohne, Kröner-Herwig, Levenson, Levenson, MacAndrew, Maier, McAdams, Mikulincer, Milrod, Nitschke, Nolen-Hoeksema, Nolen-Hoeksema, O'Brien, Rotter, Russell, Russell, Schwenkmezger, Smith, Snell, Spielberger, Sundberg, Tabachnick, Tangney, Watson, Weiss, Wilson   +54 more
core   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source