Results 151 to 160 of about 268,416 (278)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

B cells and humoral immunity in melanoma: regulatory and autoimmune-like features and implications for immunotherapy. [PDF]

Oncoimmunology
Booth L, Mahmood M, Chen X, Jacków-Malinowska J, Tsoka S, Tull TJ, Karagiannis SN.   +6 more
europepmc   +1 more source

Molecular crosstalk via exosomes in lung cancer progression

Interdisciplinary Medicine, EarlyView.
“Molecular and theranostics roles of exosomes in Lung Cancer.” Abstract Exosomes play a critical role in lung cancer metastasis, facilitating tumor progression through intercellular communication between cancer cells and the tumor microenvironment. These nanosized extracellular vesicles carry bioactive molecules such as proteins, nucleic acids, and ...
Rajib Dhar, Vinoth Kumarasamy, Brian G. Oliver, Vetriselvan Subramaniyan   +3 more
wiley   +1 more source

SARS-CoV-2 humoral immunity is associated with elevated hemoglobin A1c. [PDF]

Lab Med
Palmer-Toy DE, Yan R, Narwaney KJ, Legaspi A, Aragones M, Lam JA, Chang JM, Portugal C, Bruxvoort KJ, Glanz JM, Binswanger IA.   +10 more
europepmc   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

Systematic review and meta-analysis of humoral immunity proteins and mortality in sepsis. [PDF]

Crit Care
Villa A, Dewar F, Pisciotta W, Rai A, Kerneis S, Batum G, McDonnell T, Scully M, McHugh TD, Hilpert K, Gilroy D, de Nooijer A, Netea MG, Hedetoft M, Bermejo-Martin JF, Akatsuka M, Heinz CC, Venet F, Monneret G, Meessen J, Cheng TH, Zhang M, Caironi P, Giamarellos-Bourboulis EJ, de la Torre Terrón MC, Ebelt H, Rademaker E, Bodelsson M, Tverring J, Mi Y, Knight JC, Lindsey ML, Langley RJ, Kingsmore SF, Brealey D, Singer M, Arulkumaran N.   +36 more
europepmc   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Optimizing Humoral Immunity for Durable and Broad Protection in Flavivirus Vaccines. [PDF]

Vaccines (Basel)
Park JY, Lee HM.
europepmc   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

PTEN-mTORC2 signaling module controls antibody isotype selection and antiviral humoral immunity. [PDF]

Front Immunol
Thapa B, Lee Y, Pak S, Kim D, Kwon HJ, Lee K.   +5 more
europepmc   +1 more source