Results 41 to 50 of about 99 (99)

Home‐based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti‐BP180‐NC16a antibody

Journal of General and Family Medicine, EarlyView.
We present the case of an elderly male with bullous pemphigoid, initially negative for the anti‐BP180‐NC16a antibody, which later became positive as disease activity progressed. The patient was successfully managed at home through multidisciplinary collaboration, including a general practitioner, dermatologist, nurses, and pharmacists.
Hiromitsu Yamashita, Takayuki Ando, Hirohisa Fujikawa, Masayoshi Shiota   +3 more
wiley   +1 more source

Serum vitamin D concentration is inversely associated with matrix metalloproteinase‐9 level in periodontal diseases

Journal of Periodontology, EarlyView.
Abstract Background The aim of this study was to investigate the potential association between vitamin D deficiency and matrix metalloproteinase‐9 (MMP‐9) levels in gingival crevicular fluid (GCF) across various periodontal health and disease statuses.
Yeşim Ayhan Yıldırım, Ayla Ozturk, Fatma Doğruel, Hatice Saraçoğlu, Cevat Yazıcı   +4 more
wiley   +1 more source

Intestinal involvement in graft versus host disease in children: An overview by the ESPGHAN Gastroenterology Committee

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Graft versus host disease (GVHD) is a complication that frequently occurs after haematopoietic stem cell transplantation and concerns many children in paediatric haematology‐oncology and bone marrow transplantation departments. It can affect various organs, with the skin, gastrointestinal tract and liver being the most commonly involved.
Marina Vincent, Amit Assa, Osvaldo Borrelli, Matjaž Homan, Javier Martin‐de‐Carpi, Zrinjka Misak, Maria Giovanna Puoti, Isabelle Scheers, Sara Sila, Caterina Strisciuglio, Christos Tzivinikos, Jernej Dolinsek, Emmanuel Mas   +12 more
wiley   +1 more source

Rapid and Sustained Improvement of Lichen Planus Pemphigoides With the JAK1 Inhibitor Upadacitinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disorder characteris ed by lichenoid plaques and blister formation. Current treatments are often ineffective, and there is a lack of standardised guidelines. The disease's pathogenesis involves both T‐cell‐mediated lichenoid dermatitis and autoantibody formation, presenting ...
Louise Gueissaz, Ronald Wolf, Christoph Schlapbach   +2 more
wiley   +1 more source

Oral Administration of Trichosanthes Kirilowii Fruit Extract Ameliorates Airway Inflammation and Suppresses Th2 Cell Activities in Ovalbumin‐Sensitized Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Trichosanthes kirilowii is a plant used in traditional Chinese medicine. Its fruits, seeds, and roots can all be used medicinally. The fruit of T. kirilowii has a moistening effect on the lung for arresting cough. However, there is no scientific research to prove that the fruit of T. kirilowii can improve asthma. Herein, we evaluated whether T.
Ting‐Chi Lin, Wen‐Chung Huang, Chwan‐Fwu Lin, Wan‐Ting Chi, Shu‐Chen Cheng, Nai‐Chun Ting, Chian‐Jiun Liou   +6 more
wiley   +1 more source

Gag Gifting: The Joke and the Poke

Psychology &Marketing, EarlyView.
ABSTRACT Gag gifting is a ritual involving a gift along with a joke at the expense of the recipient (i.e., a “poke”). This study shows that gag gifting occurs frequently, at various occasions. Findings from a qualitative study illustrate the way gag gifts are purchased or handmade into unique or personalized items.
Robert M. Schindler, Pia A. Albinsson, Bidisha Burman   +2 more
wiley   +1 more source

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

Med Research, EarlyView.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li, Yuxuan Wan, Alan Jiao, Ke Jiang, Gaoyuan Cui, Jinxin Tang, Simin Yu, Zhengang Hu, Songfeng Zhao, Zhenjie Yi, Lifu Long, Yang Yang, Xuehao Cui, Chunrun Qu   +13 more
wiley   +1 more source

Retinoma: An overview

Pediatric Investigation, EarlyView.
Retinoma, a benign tumor caused by biallelic retinoblastoma gene (RB1) inactivation, offers key insights into retinoblastoma development and oncogenesis. This review explores its molecular genetics, clinical features, diagnosis, management, and potential implications for advancing the prevention and treatment of retinoblastoma.
Panagiotis N. Toumasis, Ashwin Mallipatna, Timothy W. Corson, Helen Dimaras   +3 more
wiley   +1 more source

Advancing dengue vaccine development: Challenges, innovations, and the path toward global protection

Pediatric Investigation, EarlyView.
Dengue vaccine development faces challenges, including antibody‐dependent enhancement and serotype‐specific immunity. This review highlights licensed vaccines, CYD‐TDV, TAK‐003, and Butantan‐DV, and explores strategies for achieving effective multivalent protection.
Ran Wang, Bridget Kim, Hridesh Mishra, Kevin C. Kain   +3 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source