Results 71 to 80 of about 99 (99)
TCF7‐Linked Immune Resilience: A Salutogenic Biological Warranty for Longevity
Aging Cell, EarlyView.Immune resilience as a salutogenic force to preserve healthspan and resilience to challenges. The figure was created with BioRender (https://www.BioRender.com/).
Rituparna Ghosh, Matthew J. Yousefzadeh
wiley +1 more source
Allergy, EarlyView.Fourteen genes, mainly encoding keratins, were commonly differentially expressed in both allergic and non‐allergic individuals after nasal provocation with birch pollen. The nasal provocation in birch pollen‐allergic individuals led to activation of innate immune pathways within 15–30 min and proliferation‐regulatory pathways within 60–120 min.
Srinidhi Sudharson +10 more
wiley +1 more source
Allergy, EarlyView.A pivotal Phase III DBPC adaptive trial was conducted with PQ Grass 27600 SU. The primary endpoint EAACI‐CSMS0–6 demonstrated a highly significant, clinically meaningful improvement for PQ Grass of −0.27 points (95% CI: −0.42 to −0.12), corresponding to a relative difference of −20.3% (p = 0.0005) over placebo. Highly consistent secondary endpoints and
Stefan Zielen +100 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 5, Page 829-838, May 2025.Preeclampsia fetuses show an altered profile of endothelial damage and complement biomarkers, like increased adhesion molecules, prothrombotic state, oxidative stress, and reduced complement membrane attack complex deposition on endothelial cells. Abstract Introduction Our objective was to evaluate the endothelial function profile and complement system
Alex Ramos +17 more
wiley +1 more source
A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease
Acta Ophthalmologica, EarlyView.Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia +4 more
wiley +1 more source
Anaplastic large cell lymphoma in children and adolescents
British Journal of Haematology, EarlyView.Summary Anaplastic lymphoma kinase (ALK)‐positive anaplastic large‐cell lymphoma (ALCL) accounts for >95% of ALCL cases in children and adolescents. The first description of ALCL as a CD30‐positive lymphoma in 1985 was followed by the detection of chromosomal translocations involving the ALK gene at chromosome 2p23.
Eric J. Lowe, Wilhelm Woessmann
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Brain Pathology, EarlyView.Graphical representation of the widespread white matter (blue color mask) and grey matter (cortical and deep grey matter; red color mask) demyelination in MS cases characterized by substantial inflammation of the CP (A). The presence of lesions was mainly associated with periventricular white matter and hippocampus areas (A).
R. Magliozzi +19 more
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Biological Reviews, EarlyView.ABSTRACT From blood‐sucking lice and food‐stealing gulls to pandemic‐inducing viruses and egg‐eating snakes: parasites and predators are ubiquitous in shaping ecology and evolution. Fundamental to these interactions is the way in which parasites and predators choose their victim. Here, I argue that a trade‐off between host quality and vulnerability can
Mairenn C. Attwood
wiley +1 more source
The impact of BTK knockdown on lung adenocarcinoma growth and immune response
Cancer Science, EarlyView.First study on BTK's role in LUAD progression. Low BTK expression associated with poor LUAD prognosis. Abstract This study explores the molecular role of the BTK gene in lung adenocarcinoma (LUAD) progression and patient prognosis. Using a radiomics model based on BTK expression and PET‐CT data analyzed through DeeplabV3, alongside transcriptomic and ...
Jilan Huang +6 more
wiley +1 more source