Results 81 to 90 of about 268,416 (278)
Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk [PDF]
, 2018 Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to ...Altizer, Sonia, Becker, Daniel, Bentz, Alexandra B., Camus, Melinda S., Carrera, Jorge E., Chizhikov, Vladimir E., Czirjak, Gabor A., Fenton, M. Brock, Gilbert, Amy T., Navara, Kristen J., Recuenco, Sergio E., Simmons, Nancy B., Streicker, Daniel, Volokhov, Dmitriy V. +13 morecore +3 more sourcesDiscovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission
Advanced Science, EarlyView.Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela +27 morewiley +1 more sourceINFLUENCE OF COLURIA GEOIDES (ROSACEAE) BAC ON HUMORAL IMMUNE RESPONCE
Фармация и фармакология (Пятигорск), 2015 The article presents the results of immunocorrecting properties of dry extract fractions of C. geoides (Rosaceae) for experimental immunodeficiency. Since the BAC fractions action relinquishes to the action of integral extract, the isolation of active ...S. V. Dutova, D. S. Dikhtyarov, D. R. Aukhodeev, Yu. V. Rostovtseva, M. R. Karpova +4 moredoaj +1 more sourceNutrition, diet and immunosenescence [PDF]
, 2013 Ageing is characterized by immunosenescence and the progressive decline in immunity in association with an increased frequency of infections and chronic disease.Agrawal, Agrawal, Akbar, Almanzar, Alonso, Alperovich, Alvarez-Rodriguez, Arunachalam, Azzini, Bates, Bechoua, Belisle, Belisle, Berzins, Blomberg, Bogden, Borrego, Bouwens, Bravo, Buffa, Bunout, Butcher, Calder, Camous, Canaday, Cannizzo, Carluccio, Castle, Cevenini, Chandra, Chatta, Chidrawar, Chung, Ciaramella, Clambey, Clark, Claudio Nicoletti, Colonna-Romano, Corridan, Corsini, Cortes, Cossack, Currier, De La Fuente, De la Fuente, De la Fuente, De Martinis, DelaRosa, DelaRosa, Della Bella, Dell’Agli, Dewan, Di Lorenzo, Dong, Donnini, Dorshkind, Dubey, Duchateau, Dunn-Walters, Effros, Enos, Estruch, Farges, Fateh, Faunce, Fearnley, Feart, Fietta, Flores, Fortes, Fortin, Fortin, Franceschi, Franceschi, Frasca, Frasca, Fulop, Fulop, Fulop, Fulop, Galli, Gao, Gayoso, Gebremichael, Gibson, Gibson, Gill, Gill, Ginaldi, Gomez, Goronzy, Goronzy, Guigoz, Guigoz, Hadziabdic, Hakim, Hamilton-Miller, Haynes, Haynes, Haynes, Herndler-Brandstetter, Herrero, Herrero, Hilmer, Hodkinson, Hong, Ishimoto, Jing, Kahmann, Kamal Ivory, Khan, Kowdley, Larbi, Larbi, Lasheras, Le Garff-Tavernier, Lee, Lesourd, Lesourd, Ligthart, Lung, Magrone, Mariani, Mariani, Martinez-Gonzalez, Maue, McElhaney, Merchant, Meydani, Meydani, Meydani, Meydani, Mitchell, Monagas, Murasko, Mysliwska, Mònica Maijó, Nagel, Nicoletti, Nicoletti, Nikolich-Zugich, Nova, Nova, Ogawa, Ogawa, Osler, Ouwehand, Ouwehand, Pae, Paganelli, Pallast, Pawelec, Peralbo, Peralbo, Pfister, Plackett, Plowden, Prakash, Prasad, Prasad, Prasad, Prasad, Psaltopoulou, Pérez-Cabezas, Rees, Rink, Salas-Salvado, Sarah J. Clements, Saule, Saurwein-Teissl, Scarmeas, Scarmeas, Schenkein, Schiffrin, Schiffrin, Schwaiger, Shaw, Shodell, Simon R. Carding, Sofi, Sofi, Solana, Solana, Solana, Sridharan, Steger, Stout-Delgado, Swift, Tangney, Tasat, Tortorella, Tortorella, Trichopoulou, Uyemura, Valls-Pedret, van Duin, Varas, Vasto, Vasto, Vetvicka, Vulevic, Waitzberg, Wallace, Watson, Webster, Weiskopf, Weksler, Wenisch, Wikby, Willett, Wong, Wordsworth, Wu, Yaqoob, Yaqoob, Yuan, Zanni, Zissel +217 morecore +1 more sourceSubstituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides
Advanced Science, EarlyView.This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT
Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra +13 morewiley +1 more sourceBehaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation [PDF]
, 2013 Background:
HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen ...Briggs, David, Dr., Daga, Sunil, Hamer, Rizwan, Higgins, Rob, Imray, C. (Chris), Kashi, Habib, Krishnan, Nithya S., Lam, F. T., Lowe, David Philip, Raymond, Neil T., Tan, Lam Chin, Zehnder, Daniel +11 morecore +2 more sourcesOral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis
Advanced Science, EarlyView.Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li +13 morewiley +1 more sourceImmune response of cows fed polyunsaturated fatty acids under high ambient temperatures [PDF]
, 2009 The aim of the experiment was to determine the effects of 2 different fat supplementations on immune functions of dairy cows under high ambient temperatures.Albenzio, M, Caroprese, M, Entrican, G, Marzano, A, Sevi, A, Wattegedera, S +5 morecore +1 more sourcePD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy
Advanced Science, EarlyView.The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou +24 morewiley +1 more sourceHumanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma
Advanced Science, EarlyView.CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen +13 morewiley +1 more source