Results 131 to 140 of about 68,775 (285)

Humour styles and psychosocial adjustment in junior school pupils [PDF]

open access: yes, 2017
It has been proposed that four main styles of humour exist. Research with adults and older children has identified links between these four styles of humour and psychosocial adjustment. Whilst adaptive humour styles have been found to be positively related to adjustment, maladaptive humour styles have been found to be negatively related.
openaire  

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li   +22 more
wiley   +1 more source

'It’s about expecting the unexpected’: Live stand-up comedy from the audiences’ perspective [PDF]

open access: yes, 2011
Copyright @ 2011 The Authors.A dearth of research exists that examines live stand-up comedy from the audiences’ perspective. This empirical article redresses this neglect by examining the appeal of live stand-up comedy to audiences and revealing their ...
Myers, L
core  

Humour Styles and Negative Intimate Relationship Events

open access: yes, 2014
Research has shown that humour is associated with satisfaction and conflict management in dyadic relationships, such as friendships and romantic relationships. However, humour is not inherently positive or negative in itself. The function of humour depends on the style through which it is expressed.
openaire   +1 more source

DSG2+ Cancer Stem Cells Co‐Located With FAP+ Myofibroblasts in the Tumor Boundary That Determines the Efficacy of Immunotherapy in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Cancer stem cells (CSCs) in non‐small cell lung cancer display pronounced plasticity and spatial heterogeneity. By integrating single‐cell and spatial transcriptomics, this study defines a DSG2‐associated CSC program and reveals a tumor‐margin niche formed with FAP+ myofibroblasts.
Guangyu Fan   +8 more
wiley   +1 more source

Jutustuste kasutamine Keenia jumalateenistustel

open access: yesMäetagused, 2000
Religious communication uses a number of techniques or styles, for instance including films, literature, songs/poetry, and dance. In the verbal communication of a religious message, the speaker can employ proverbs, riddles, emphasis etc.
Ezekiel B. Alembi
doaj  

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

open access: yesAdvanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang   +10 more
wiley   +1 more source

Stress, Anxiety and Depression in First-year Medical Undergraduates and Coping Strategies Employed during COVID-19-induced Online Learning: A Cross-sectional Study from North India

open access: yesJournal of Medical Evidence
Background: The COVID-19 pandemic, due to its rising uncertainties, was expected to negatively impact the overall psychological functioning of students undergoing first year of medical professional education with changing teaching styles and ...
Rashmi Malhotra   +6 more
doaj   +1 more source

Promoting engagement and learning in first year university studies: The role of personalisation [PDF]

open access: yes, 2011
Student engagement in higher education can be conceptualised as involving three components: students’ social needs and circumstances, the cognitive characteristics of academic studies, and the prevailing institutional ethos or philosophy that specifies ...
Fraser, Cath   +2 more
core  

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

open access: yesAdvanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin   +19 more
wiley   +1 more source

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