Results 101 to 110 of about 36,080 (282)
Abstract Background Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin gene on chromosome 4, leading to progressive cognitive decline, motor impairment, and functional disability. Although balance impairment is recognized in HD, its onset and evolution with disease stage remain poorly ...
Japleen Kaur +6 more
wiley +1 more source
Novel methods and therapeutic approaches of diagnosis and treatment of Huntington's disease [PDF]
Andreas Weiss
openalex +1 more source
Centrally and peripherally altered glucose transporters: is it time to revisit energy deficiency as a potential treatment strategy in Huntington's disease? [PDF]
Maria Björkqvist
openalex +1 more source
Huntington's Disease and Huntington's Disease‐like 2 (HDL2) in Martinique
ABSTRACT Background Huntington's Disease‐like 2 (HDL2), caused by a CAG repeat expansion in JPH3, closely resembles HD. All reported HDL2 patients to date have some African ancestry. While both disorders exist in the Caribbean, their relative frequency and clinical characteristics remain largely unknown.
Ignacio Antolin‐Sanfeliz +8 more
wiley +1 more source
J P, Vonsattel, M, DiFiglia
openaire +2 more sources
ABSTRACT Background Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin gene on chromosome 4, leading to progressive cognitive decline, motor impairment, and functional disability. Falls represent the leading cause of nursing home placement in HD.
Japleen Kaur +7 more
wiley +1 more source
Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients
Johannes K. Ehinger +4 more
openalex +2 more sources
Abstract Background Multidisciplinary care has been advocated for Juvenile‐onset Huntington's Disease but there has been no detailed analysis of this. Objectives To evaluate the current economic costs of providing health care for patients with Juvenile‐onset Huntington's disease (JoHD) and to model the effects and economic costs of providing a ...
Tracey A. Young +5 more
wiley +1 more source

