Results 231 to 240 of about 36,080 (282)

Examining Balance and the Likelihood of Falls in Huntington's Disease. [PDF]

Clin Park Relat Disord
Youhanan N, Kaur J, Hall A, Bagga K, Patel S, Sidhu A, Alskaf R, Shaik Z, Gilbert PE, Goble DJ, Corey-Bloom J.   +10 more
europepmc   +1 more source

Long‐term amyloid PET and MRI outcomes in a menopausal hormone therapy trial

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Associations of short‐term use of menopausal hormone therapy (mHT) with Alzheimer's disease (AD) and structural magnetic resonance imaging (MRI) biomarkers were investigated 10 years after an mHT trial. METHODS Recently menopausal women with good cardiovascular health were randomized to oral conjugated equine estrogens (oCEE) or ...
Kejal Kantarci, Firat Kara, Nirubol Tosakulwong, Angela J. Fought, Christopher G. Schwarz, Matthew L. Senjem, June Kendall‐Thomas, Paul Min, Val J. Lowe, Clifford R. Jack, Ekta Kapoor, Julie A. Fields, Kent R. Bailey, Taryn T. James, Laura Faubion, Rogerio A. Lobo, JoAnn E. Manson, Lubna Pal, Dustin B. Hammers, Eliot A. Brinton, Michael Malek‐Ahmadi, Marcelle I. Cedars, Frederick N. Naftolin, Nanette Santoro, Virginia M. Miller, Sherman M. Harman, N. Maritza Dowling, Carey E. Gleason   +27 more
wiley   +1 more source

Dysfunctions of sleep and the circadian rhythm in Huntington's disease. [PDF]

Front Neurol
Kaczmarska P, Rudzińska-Bar M.
europepmc   +1 more source

APP‐mediated intracellular signaling rescues sleep impairment and blood–brain barrier leakage in Alzheimer's disease mouse model

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Amyloid beta peptide (Aβ) accumulation in the brain is an Alzheimer´s disease (AD) hallmark. Sleep disturbances hamper Aβ production and clearance, thereby exacerbating the Aβ burden. The mechanisms involved remain unclear. We reported that amyloid precursor protein (APP), the Aβ source, possesses intracellular signaling that ...
Clémentine Puech, Anjana Sadanand, Neil Coleman, Marilyn Ikhane, Mohammad Badran, Rong Wang, David Gozal, Angèle T. Parent   +7 more
wiley   +1 more source

Exploring Cordycepin as a Neuroprotective Agent in Huntington's Disease: In Vitro and In Vivo Insights. [PDF]

Pharmacol Res Perspect
Tung CW, Chan SC, Cheng PH, Chen YC, Wu PM, Lin WC, Chen RJ, Huang BM, Yang SH.   +8 more
europepmc   +1 more source

Targeted blood proteome profiling using NULISAseq identifies a high‐performance biomarker panel for Aβ pathology quantification and staging

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION While current blood‐based biomarkers for Alzheimer's disease (AD) are effective for determining amyloid beta (Aβ) pathology positivity/negativity, they are insufficient for quantifying Aβ plaque deposition. METHODS We profiled 325 plasma proteins in a Hong Kong Chinese cohort using the Nucleic Acid Linked Immuno‑Sandwich Assay ...
Wenyue Zheng, Yuanbing Jiang, Hiu Yi Wong, Wan Wa Wong, Lily K. W. Cheng, Elaine Y. L. Cheng, Bonnie W. Y. Wong, Ronnie M. N. Lo, Siu Ki Leung, Fanny C. Ip, Jacqueline K. Y. Yuen, Yat Fung Shea, Wai Ming Wong, Chun Keung Shum, Hok Man Wai, Vincent C. T. Mok, Timothy C. Y. Kwok, Kin Y. Mok, Amanda Heslegrave, John Hardy, Henrik Zetterberg, Amy K. Y. Fu, Nancy Y. Ip   +22 more
wiley   +1 more source

Decreased Physical Activity as an Early Digital Biomarker in Huntington's Disease: A One‐Year Observational Study

Brain and Behavior, Volume 16, Issue 2, February 2026.
Physical Activity: Early Biomarker in Huntington's Disease. ABSTRACT Introduction Huntington's disease (HD) is a neurodegenerative disorder characterised by motor dysfunction, cognitive impairment, and psychiatric disturbances. This study analyzed the relationship between clinical characteristics, sarcopenia, and physical activity (PA) levels in HD ...
Lucía Simón‐Vicente, Sara Calvo, Natividad Mariscal, Ignacio Muñoz‐Siscart, Dolores Diaz‐Piñeiro, Jéssica Rivadeneyra, Esther Cubo   +6 more
wiley   +1 more source

Late-Onset Huntington's Disease in Mexico: A Retrospective Study. [PDF]

Cureus
Ochoa-Morales A, Beutelspacher-Fernandez K, Jara-Prado A, Yescas-Gómez P, Guerrero-Camacho JL, Pérez-Pacheco NJ, Dávila-Ortiz de Montellano D, Ramírez-García MÁ.   +7 more
europepmc   +1 more source