Results 251 to 260 of about 10,552,439 (323)

Eye manifestations in Huntington's disease: an update on the potential of ocular biomarkers. [PDF]

J Neurol
Woods WA, Barker RA.
europepmc   +1 more source

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

24S-Hydroxycholesterol: A potential brain-derived biomarker of Huntington’s Disease

Asgari MA, Langbehn DR, Skibinski DOF, Lee R, Griffiths WJ, Wang Y.   +5 more
europepmc   +1 more source

Modest rescue of RBFOX1 splicing function attenuates Huntington's disease features. [PDF]

Mol Med
Lozano-Muñoz D, Elorza A, Lucas-Santamaría M, Santos-Galindo M, Parras A, Lucas JJ.   +5 more
europepmc   +1 more source

I'll Be Dammed: Efficiency and Cost‐Analysis of a Rehabilitated Prehispanic Dam in the Andes

Geoarchaeology, Volume 41, Issue 4, July/August 2026.
ABSTRACT Within archaeology there is a growing shift away from the purely aesthetic towards making the past relevant to present and future needs and demands. The Past Water Futures project charts the impact of ancient dam rehabilitation on climate change‐induced water scarcity in the North Central Andes.
Kevin Lane, Ricardo Flores‐Marquez, Rodrigo J. Puga‐Calderón, Pedro Gonzalez, Mario Advíncula, Alexander Herrera   +5 more
wiley   +1 more source

Silymarin Modulates 3‐Nitropropionic Acid‐Induced Oxidative Neurotoxicity and Apoptosis Through the Inhibition of TRPV1 Channel in Mouse Brain and Hippocampal Neurons

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
Silymarin attenuates 3‐nitropropionic acid–induced oxidative stress and apoptosis in mouse brain and hippocampal neurons by inhibiting TRPV1 channel activation. TRPV1 blockade reduces Ca2+ influx, mitochondrial ROS generation, and caspase‐mediated cell death, conferring neuroprotection.
Abdulsamed Kükürt, Ömer Faruk Başer
wiley   +1 more source

Molecular Profiling of Extracellular Vesicles Isolated from Boar Reproductive Fluids

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs) are small membrane‐bound structures that facilitate intercellular communication in the reproductive system, modulating gamete maturation, capacitation, immunomodulation and fertilization. Despite pigs’ high relevance as a biomedical model, many aspects of EV biology remain poorly understood.
Veronika Kraus, Barbora Doleckova, Michaela Frolikova, Ondrej Sanovec, Daniela Spevakova, Zuzana Pilsova, Aneta Pilsova, Katerina Komrskova, Ondrej Simonik, Pavla Postlerova   +9 more
wiley   +1 more source

Cellular Senescence and Aging: Mechanisms, Disease Convergence, and Therapeutic Frontiers

MedComm, Volume 7, Issue 7, July 2026.
This schematic illustrates the hierarchical and interconnected nature of the primary molecular hallmarks of aging. The progression of aging is driven by a convergence of intrinsic molecular insults. Within the nucleus, genomic instability and telomere attrition trigger persistent DDR, accompanied by extensive epigenetic alterations.
Guowei Cai, Jia Ren, Li Wang, Yingying Wu, Huirui Wang, Xiaomeng Cao, Hao Shang, Xuben Hou, Yujiu Wang, Haibo Xue, Ting Dong   +10 more
wiley   +1 more source

Late-Onset Huntington's Disease in Mexico: A Retrospective Study. [PDF]

Cureus
Ochoa-Morales A, Beutelspacher-Fernandez K, Jara-Prado A, Yescas-Gómez P, Guerrero-Camacho JL, Pérez-Pacheco NJ, Dávila-Ortiz de Montellano D, Ramírez-García MÁ.   +7 more
europepmc   +1 more source

Genetic and Pathological Testing Attitudes for Parkinson's Disease in At‐Risk Relatives

Movement Disorders Clinical Practice, Volume 13, Issue 7, Page 1681-1689, July 2026.
Abstract Background Parkinson's disease (PD) is increasingly recognized as a neurodegenerative disorder with a broad clinical spectrum and diverse biomarkers enabling early detection. α‐synuclein seed amplification assays (SAA) and genetic testing now allow identification of PD pathology in asymptomatic individuals.
Tal Weil, Anat Mirelman, Roy N. Alcalay, Nurit Omer, Penina Ponger, Avner Thaler   +5 more
wiley   +1 more source