Results 291 to 300 of about 93,886 (309)

Pridopidine in early-stage manifest Huntington's disease: a phase 3 trial. [PDF]

Nat Med
Reilmann R, Feigin A, Rosser AE, Kostyk SK, Saft C, Cohen Y, Schuring H, Hand R, Tan AM, Chen K, Feng W, Navon-Perry L, Cruz-Herranz A, Syltevik C, Boot D, Squitieri F, Kayson E, Mehra M, Goldberg YP, Geva M, Hayden MR, PROOF-HD study investigators.   +21 more
europepmc   +1 more source

Non‐Directiveness and Authenticity in the Predictive Genetic Clinic

Sociology of Health &Illness, Volume 48, Issue 2, February 2026.
ABSTRACT The predictive genetic clinic is a space where counsellors use non‐directive counselling to facilitate asymptomatic patients at risk of carrying a dominantly inherited disease access a predictive genetic test. The social science literature has a history of examining practices within this clinic, but with little attention from the sociology of ...
Shane Doheny, Rebecca Dimond, Lisa Ballard, Anneke Lucassen, Angus Clarke   +4 more
wiley   +1 more source

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.
Cannabidiol and cannabigerol suppress maximal electroshock seizures. Cannabidiol and cannabigerol show similar dose–response properties. Both cannabinoids show no toxicity at effective doses. ABSTRACT Current antiseizure therapy for epilepsy is only effective in about 70% of the patient population.
Han Zhong Zhou, Brian Wayne Scott, Yagoda Izabela Oleksak, Willets McIntyre Burnham   +3 more
wiley   +1 more source

Dysregulation of melatonin rhythm in Parkinson's and Huntington's disease: a systematic review and meta-analysis. [PDF]

Front Aging Neurosci
Suram RP, Fatima R, Madhuvilakku R, Jung JH, Kim SJ, Hong Y.   +5 more
europepmc   +1 more source

Living with Risk, Aging with Uncertainty: A Narrative Review of Health and Genetic Vulnerability in Huntington's Disease. [PDF]

Biomedicines
Muñoz-Ortega AV, Conde Caballero D, Mariano Juárez L.   +2 more
europepmc   +1 more source

Astrocytic noncanonical WNT5B signaling modulates extracellular matrix remodeling and neuropathology in Huntington's disease. [PDF]

Signal Transduct Target Ther
Nguyen PTT, Yousefian-Jazi A, Hyeon SJ, Lee S, Kim SC, Park U, Jeong Y, Kim S, Kim S, Kim Y, Ryu HL, Lee KE, Stein TD, Myers RH, Hwang EM, Lee J, Ryu H.   +16 more
europepmc   +1 more source