Results 121 to 130 of about 36,029 (296)

Fuel on the Invention Funnel: Technology Licensing-in, Antecedents and Invention [PDF]

open access: yes
In this paper, we examine the impact of technology licensing-in on firm invention performance. Studying a sample of 266 licensees and matched non-licensees using a two-part model specification, we find that licensees are more likely to introduce ...
Mats Magnusson   +3 more
core  

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Structural insights on anti-biofilm mechanism of heated slightly acidic electrolyzed water technology against multi-resistant Staphylococcus aureus biofilm on food contact surface

open access: yesFood Science and Human Wellness
Slightly acidic electrolyzed water (SAEW) has proven to be an efficient and novel sanitizer in food and agriculture field. This study assessed the efficacy of SAEW (30 mg/L) at 40 ℃ on the inactivation of foodborne pathogens and detachment of multi ...
Pianpian Yan   +9 more
doaj   +1 more source

The first hurdle

open access: yes
The First Hurdle dives into the story of the incredible people-led activism from the East Brisbane community, in the face of their local park and school being demolished to make way for the Brisbane 2032 Olympics.
Stubbs, Lauren
core  

Interfacial Engineering by Metallic Ions and Organic Ammonium Ligand Passivation for Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
A synergistic approach using phenethylammonium iodide (PEAI) and antimony iodide (SbI3) enhances the operational stabilities of perovskite solar cells by providing p‐type doping effect, suitable band energy alignment, reduced defect density, and minimized surface ion vacancies in the perovskite films.
Abraham Adenle   +17 more
wiley   +1 more source

Technology-Specific Hurdle Rates for Energy System Optimization Models

open access: yes
This work presents a methodology to evaluate technology-specific hurdle rates for energy system optimization models. Hurdle rates are usually assumed through educated guesses by energy system modellers, while they are estimated here by adopting the ...
Laera, Silvia   +5 more
core  

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

open access: yesAdvanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller   +6 more
wiley   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

open access: yesAdvanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang   +11 more
wiley   +1 more source

Standardization and Preservation of Sugarcane Juice by Hurdle Technology

open access: yes, 2018
Preservation of sugarcane juice was examined to reduce the spoilage and to increase the shelf life ofthe juice using hurdle technology. The intelligent use of combinations of different preservation factors ortechniques to make a product shelf-stable, to ...
Bharathidasan, R., Rajendran, P.
core  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

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