Results 181 to 190 of about 8,346,214 (299)

Usage of bacteriocins in hurdle technology

Turkish Bulletin of Hygiene and Experimental Biology, 2014
openaire   +1 more source

Green simultaneous quantification of levodopa, carbidopa, and benserazide in anti-Parkinson's tablets by ATR-FTIR spectroscopy combined with hurdle modelling and machine learning. [PDF]

RSC Adv
Nguyen MH, Nguyen TD, Duong HA, Pham HV.
europepmc   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

Associations between accelerometer-assessed occupational and leisure-time sitting and self-reported cognitive dysfunction in Swedish middle-aged adults: a cross-sectional analysis from the SCAPIS study. [PDF]

BMC Public Health
Bergman F, Boraxbekk CJ, Hettiarachchi P, Svartengren M, Wennberg P, Fortuin-de Smidt M.   +5 more
europepmc   +1 more source

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

Advanced Science, EarlyView.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang, Zhanzhi Liu, Ying Xu, Mingjing Sun, Guangzhen Zhou, Deming Rao, Xiaoqian Chen, Sheng Wang, Zhigang Li, Yan Huang, Jing Wu   +10 more
wiley   +1 more source

Evaluating statistical models for overdispersed multiomics data: a multiplex immunofluorescence case study. [PDF]

Am J Epidemiol
Thomas CE, Wesselink E, Takashima Y, Huyghe JR, Buchanan DD, Grant RC, Dias Costa A, Ugai T, Ogino S, Nowak JA, Peters U, Phipps AI, Hsu L.   +12 more
europepmc   +1 more source

Effects of gamma irradiation and silver nano particles on microbiological characteristics of saffron, using hurdle technology. [PDF]

Indian J Microbiol, 2012
Hamid Sales E, Motamedi Sedeh F, Rajabifar S.   +2 more
europepmc   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source

Epidemiology of <i>Eustrongylides</i> sp. Infection in <i>Triplophysa strauchii</i>: Temporal Dynamics and Risk Factors. [PDF]

Vet Sci
He Y, Chen M, Yu C, Wang X, Li X, Guo W.
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source