Results 91 to 100 of about 1,306,732 (153)

Developing and Applying a Yeast Model of Hutchinson-Gilford Progeria Syndrome

The human premature aging disorder Hutchinson-Gilford progeria syndrome can, by virtue of its single molecular cause, be introduced to other living systems which allows for a more controlled and nuanced study of the disease.
Chivers, Christopher Patrick
core  

Lonafarnib clinical trials demonstrate uncoupling of the muscle-bone unit in Hutchinson-Gilford Progeria Syndrome. [PDF]

J Bone Miner Res
Kreienkamp RJ, Gordon LB, Ehrbar R, Pendleton A, Schiferl DJ, Lyass A, Kleinman ME, Snyder BD, Gordon CM.   +8 more
europepmc   +1 more source

Correction: Hutchinson-Gilford progeria syndrome alters the endothelial genetic response to laminar shear stress. [PDF]

Front Physiol
Kennedy CC, Carter JL, Truskey GA.
europepmc   +1 more source

Epidural hematoma in a pediatric patient with Hutchinson-Gilford progeria syndrome: management considerations: a case report. [PDF]

Chin Neurosurg J
Ozmarasali AI, Sivas ZZ, Uguz I, Oto A.
europepmc   +1 more source

HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling. [PDF]

Nat Commun
Hu Q, Sun Q, Xiang W, Zhou Z, Sun H, Hu Y, Yang L, Wang C, Zhang F, Cong Y, Zhang Y, Xiao Y, Cong X.   +12 more
europepmc   +1 more source

A study on the nutritional status and body composition of children with Hutchinson-Gilford progeria syndrome. [PDF]

Orphanet J Rare Dis
Yu Q, Wang J, Fu H, Mao J.
europepmc   +1 more source

Mutation-agnostic base editing of the progerin farnesylation site rescues Hutchinson-Gilford progeria syndrome phenotypes in neuromuscular organoids. [PDF]

Nat Commun
Kim DW, Kwon EJ, Jeon BJ, Kwon DH, Jang G, Yoon Y, Hwang Y, Lee H, Cha HJ.   +8 more
europepmc   +1 more source

Author Correction: Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome. [PDF]

Commun Biol
Kang SM, Yoon MH, Ahn J, Kim JE, Kim SY, Kang SY, Joo J, Park S, Cho JH, Woo TG, Oh AY, Chung KJ, An SY, Hwang TS, Lee SY, Kim JS, Ha NC, Song GY, Park BJ.   +18 more
europepmc   +1 more source

Anaesthetic management of paediatric patient with Hutchinson-Gilford progeria syndrome: A case report. [PDF]

Indian J Anaesth, 2023
Oliveira FJM, Araújo IT, Gomes JLUM, França MA.   +3 more
europepmc   +1 more source

Author Correction: p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson-Gilford progeria syndrome. [PDF]

Nat Cell Biol
Son SM, Park SJ, Breusegem SY, Larrieu D, Rubinsztein DC.   +4 more
europepmc   +1 more source